ISSN: 1859 - 2872
Investigation on antibiotic use in the treatment of skin and soft tissue infections at University Medical Center Ho Chi Minh City
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Abstract
Objective: To investigate pathogens and antibiotic use, to evaluate the rationality of antibiotic indication for common skin and soft tissue infections (SSTIs) as well as to identify factors that may be attributed to treatment response at University Medical Center Hochiminh City (UMC HCMC). Subject and method: A cross - sectional study was conducted in 136 patients diagnosed with abscess, cellulitis, or diabetic foot infection (DFI) and indicated with antibiotics for 3 days or more from 01/01/2019 to 31/12/2019 at UMC HCMC. Result: The rate of abscess, cellulitis, and DFI were 40.4%, 35.3%, and 24.3%, respectively. Methicillin - resistant Staphylococcus aureus (MRSA) was the most prevalent pathogen isolated (39.1%). Appropriate antibiotic indication was observed in 25% of patients treated with empirical antibiotic therapy and 58.5% of patients treated with pathogen - specific therapy. Factors related to prolonged hospitalization included incision and drainage, Charlson comorbidity index (CCI), MRSA infection, and the isolation of pathogens. Conclusion: We observed a high proportion of broad - spectrum antibiotics as empirical therapy, which was also the predominant factor associated with inappropriate antibiotic indication at the site of study.
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References
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