ISSN: 1859 - 2872
Treatment results and some factors related to Japanese encephalitis in children at Vietnam National Children's Hospital (2/6/2018 - 2/9/2019)
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Abstract
Objective: To describe treatment results and some factors related to Japanese encephalitis patient's sequelae at the National Children's Hospital from June 2nd, 2018 to September 2nd, 2019. Subject and method: A cross-sectional description of 93 patients with Japanese encephalitis admitted to the Department of Infectious Diseases at National Children's Hospital from June 2nd, 2018 to September 2nd, 2019. Result: The most common age group was 5 - 10 years old (41%), the highest number of patients was in June (49.4%). There were no fatal, 48% of patients completely recovered without leaving sequelae, 52% of patients had sequelae after discharge, of which the most was motor sequelae (accounting for 23% of the total) number of patients), 2nd most psychomotor sequelae (20% of total patients), mental sequelae (9% of total patients). History of inadequate vaccination OR = 1.575 (95%CI: 1.091 - 2.272), stiff neck sign OR = 3.036 (95%CI: 1.152 - 8.002), Kernig OR = 4.659 (95%CI: 1.411 - 15.382), Brudzinski OR = 14.667 (95%CI: 1.820 - 118.224), impaired consciousness OR = 4.469 (95%CI: 1.333 - 14.98), motor paralysis OR = 12.88 (95%CI: 3.507 - 47.308), cranial MRI image brain showing hippocampal lesions OR = 6.296 (95%CI: 2.098 - 18.895) and hyperintensity pattern on T2 pulse OR = 5.727 (95%CI: 1.933 - 16.971) were associated factors to the sequel state of JE patient (p<0.05). The respiratory failure wasn’t related to the sequelae of JE patients (p>0.05). Conclusion: Japanese encephalitis B had high sequelae. History of inadequate vaccination, meningoencephalitis, cognitive dysfunction, motor paralysis, along with cranial MRI showing thalamus and T2 hyperintensity lesions were associated factors to sequelae of patients with JE.
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References
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