ISSN: 1859 - 2872
Relationship between H-FABP with some cardiovascular events and mortality during the in-hospital stay and 30-day follow-up after STEMI
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Abstract
Objective: To research on the relationship between H-FABP with cardiovascular events and mortality prognosis during the in-hospital stay and 30-day follow-up after STEMI. Subject and method: A descriptive, prospective study, 146 STEMI patients were admitted to 175 Military Hospital from 09/2017 to 06/2020; quantification of H-FABP based on turbidimetric immunoassay (Randox). Result: H-FABP of the in-hospital stay and 30-day follow-up major cardiovascular events and death group was higher than those of the other group (p<0.01). H-FABP had good value in the prediction of in-hospital mortality with AUC = 0.729, 95%CI: 0.63 - 0.83, p<0.01, cut-off point was 62.75ng/ml. Combining H-FABP with routine cardiovascular markers or with TIMI or GRACE scores both increased the AUC value in mortality prognosis during hospital stay with AUC: 0.746 - 0.856, p<0.01. During the 30-day follow-up period, the group of patients at the time of admission with H-FABP concentration > 62.75ng/ml would have a higher risk of major cardiovascular events than the other group, with HR = 8.66, 95%CI: 1.04 - 72.97, p<0.05. Conclusion: H-FABP had a good prognosis value of the risk of mortality and major cardiovascular events during the in-hospital stay and 30-day follow-up after STEMI.
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References
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