Research characteristics of prosthesis - patient mismatch after aortic valve replacement for aortic stenosis at 108 Military Central Hospital

  • Ngo Tuan Anh 108 Military Central Hospital
  • Nguyen Truong Giang Vietnam Military Medical University

Main Article Content

Keywords

Patient prosthesis mismatch (PPM), aortic stenosis (AS)

Abstract

Objective: To comment on patient - prosthesis mismatch (PPM) characteristics after aortic valve replacement for aortic stenosis and some related factors. Subject and method: 67 patients received aortic valve replacement for aortic stenosis at 108 Military Central Hospital during 2010-2020. Prospective descriptive study with variables: PPM status and related factors such as comorbidities, gradient, NYHA and LVMI. Result: Mild PPM accounts for 1.5 - 20% during 48 months, no moderate and severe PPM. Factors associated with PPM included female and diabetes (p<0.05), hypertension, valve size (21 - 23); biological valve type was not related (p>0.05). Mean gradient pressure was strongly correlated with PPM by quadratic linear regression. PPM increased NYHA grade of heart failure (p<0.05) and reduced LVMI to normal after surgery (p<0.05). Conclusion: Choosing the right prosthetic valve for the patient is very important, affecting the improvement of symptoms and left ventricular morphology after surgery.

Article Details

References

1. Man DL et al (2015) Braunwald’s heart disease: A textbook of cardiovascular medicine, 10th edition. Saunders, an imprint of Elsevier Inc, Philadelphia.
2. Dayan V, Vignolo G, Soca G et al (2015) Predictors and outcomes of prosthesis-patient mismatch after aortic valve replacement. JACC Cardiovasc Imaging 9(8): 924-933.
3. Nishimura RA, Otto CM, Bonow RO et al (2017) AHA/ACC Guideline for the management of patients with valvular heart disease. Journal of the American College of Cardiology 63(22): 57-185.
4. Ramachandran A (2017) Classification and diagnosis of diabetes, American diabetes association. Diabetes Care 40(1): 11-24.
5. Bilkhu R, Jahangiri M, Otto CM (2019) Patient-prosthesis mismatch following aortic valve replacement. Heart 105(1): 28-33.
6. Gou L, Zheng J, Chen L et al (2017) Impact of prosthesis - patient mismatch on short - term outcomes after aortic valve replacement: A retrospective analysis in East China. Journal of Cardiothoracic Surgery 12(42): 1-6.
7. Pibarot P, Dumesnil JG (2006) Prosthesis-patient mismatch: Definition, clinical impact and prevention. Heart 92(8): 1022-1029.
8. Ryomoto M, Mitsuhiro M, Yamamura M et al (2008) Patient-prosthesis mismatch after aortic valve replacement in the elderly. General Thoracic and Cardiovascular Surgery 56: 330-334
9. Freitas-Ferraz AB (2019) Aortic stenosis and small aortic annulus: Clinical challenges and current therapeutic alternatives. Circulation 139(23): 2685-2702.
10. Pibarot P (2018) Imaging for predicting and assessing prosthesis-patient mismatch after aortic valve replacement. JACC Cardiovasc Imaging 12(1): 149-162.