Research characteristics of left ventricular mass index after aortic valve replacement for aortic stenosis at 108 Military Central Hospital

  • Ngo Tuan Anh 108 Military Central Hospital
  • Nguyen Truong Giang Vietnam Military Medical University

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Keywords

Left ventricular mass index (LVMI), aortic valve replacement (AVR)

Abstract

Objective: To comment on changes in left ventricular mass index and related factors in patients with aortic valves replacement for aortic stenosis at 108 Military Central Hospital. Subject and method: 67 patients underwent aortic valves replacement for aortic stenosis. Descriptive study, no control with variables: LVMI, probability of LVMI returning to normal after surgery, R analysis of correlation factors such as hypertension, diabetes, PPM... Result: LVMI decreased significantly after surgery with p<0.05. The estimated probability of LVMI returning to normal at month 24 was 55%, month 48 was 37.9%. LVMI (medium - term follow-up) was linearly correlated with preoperatively (r = 0.44, p<0.001). Hypertension and PPM significantly affected LVMI with R² = 0.244 and LVMI group to normal by 3.62 times compared with hypertensive group (p<0.05). Conclusion: After valve replacement LVMI decreased over time, the probability of LVMI returning to normal was closely related to preoperative LVMI, hypertension and PPM.

Article Details

References

1. Đỗ Doãn Lợi (2014) Hẹp van động mạch chủ. Hội Tim mạch học Việt Nam.
2. Phạm Nguyễn Vinh (2013) Bệnh học tim mạch. Nhà xuất bản Y học, tập 2.
3. Man DL et al (2015) Braunwald’s heart disease: A textbook of cardiovascular medicine, 10th edition. Saunders, an imprint of Elsevier Inc, Philadelphia.
4. Nishimura, Rick A et al (2017) 2017 AHA/ACC focused update of the 2014 AHA/ACC guideline for the management of patients with valvular heart disease: A report of the American College of Cardiology/American Heart Association Task Force on Clinical Practice Guidelines 70(2): 252-289.
5. Kinno M, Waller AH, Gardin JM (2016) Approaches to echocardiographic assessment of left ventricular mass: What does echocardiography add? JACC Journals on ACC.org.
6. Gaudino M (2005) Survival after aortic valve replacement for aortic stenosis: Does left ventricular mass regression have a clinical correlate?. Eur. Heart J 26(1): 51-57.
7. Mack MJ (2015) 5-year outcomes of transcatheter aortic valve replacement or surgical aortic valve replacement for high surgical risk patients with aortic stenosis (PARTNER 1): A randomised controlled trial. Lancet 385(9986): 2477-2484.
8. Roscitano A (2005) Indexed effective orifice area after mechanical aortic valve replacement does not affect left ventricular mass regression in elderly. European journal of cardio-thoracic surgery 29(2): 139-143.
9. Lund O, Emmertsen K, Dørup I et al (2003) Regression of left ventricular hypertrophy during 10 years after valve replacement for aortic stenosis is related to the preoperative risk profile. Eur. Heart J 24(15): 1437-1446.
10. Mehta RH, Bruckman D, Tsai T et al (2001) Implications of increased left ventricular mass index on in-hospital outcomes in patients undergoing aortic valve surgery. J. Thorac. Cardiovasc Surg 122(5): 919-928.