Clinical and endoscopic characteristics of peptic ulcer bleeding in patients taking antithrombotic drugs

  • Nguyen Duc Ninh 108 Military Central Hospital
  • Thai Doan Ky 108 Military Central Hospital
  • Nguyen Hai Ghi 108 Military Central Hospital
  • Nguyen Ngoc Quang 108 Military Central Hospital

Main Article Content

Keywords

Peptic ulcer gastrointestinal bleeding, antithrombotic drugs

Abstract

Objective: To study the clinical and endoscopic characteristics of peptic ulcer bleeding in patients taking antithrombotic drugs. Subject and method: A cross-sectional descriptive study on 49 patients with peptic ulcer bleeding who used antithrombotic drugs at 108 Military Central Hospital. Result: The mean age of patients was 68.98 ± 10.54 years, most of them were taking antiplatelet drugs (65.3%). The most common clinical symptoms were melena (73.5%) and hematemesis (44.8%). Upper GI endoscopy showed gastric or duodenal ulcers with Forrest IIc/III accounted for the highest percentage. The risk of gastrointestinal bleeding in patients using antiplatelet agents was 4.03 with 95%CI ranging from 1.16 to 10.00 (p<0.05). Conclusion: Peptic ulcer bleeding in patients receiving antithrombotic drugs occurs mostly among elderly patients, most are mild and moderate bleeding. Being treated with antiplatelet agents increases the risk of gastric ulcer bleeding up to 4.03 times, compared with that of non-antiplatelet antithrombotic drugs.

Article Details

References

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Published
Jul 31, 2021
DOI: https://doi.org/10.52389/ydls.v16i5.801
Issue
Volume 16 - No 5/2021
Section
Articles
How to Cite
NinhN. D., KyT. D., GhiN. H., & QuangN. N. (2021). Clinical and endoscopic characteristics of peptic ulcer bleeding in patients taking antithrombotic drugs . Tạp Chí Y Dược lâm sàng 108, 16(5). https://doi.org/10.52389/ydls.v16i5.801