Đánh giá hiệu quả điều trị viêm nha chu có hỗ trợ laser diode 810nm lên kiểm soát đường huyết, protein phản ứng C và các cytokine viêm ở bệnh nhân đái tháo đường týp 2

Abstract

Objective: The aim of this study was to investigate the effect periodontal therapy with diode laser 810nm on the circulating of C-reactive protein (CRP), interleukin-1β (IL), IL-6, tumor necrosis factor-α (TNF-α) and on the glycated haemoglobin (HbA1c) in the type 2 diabetes mellitus (DM2) patients. Subject and method: Thirty five DM2 patients with periodontitis were enrolled in this study. Periodontal clinical parameters, included gingival index (GI), plaque index (PI), probing pocket depth (PD), clinical attachment level (CAL) and HbA1c, were evaluated before and 3 months. Blood samples were assessed for the level of CRP, IL-1β, IL-6, TNF-α and HbA1c. All parameters were evaluated before and 1 months after periodontal treatment with diode laser 810nm. Result: All clinical parameters were significantly improved 3 month after periodontal therapy. Level of systemic inflammation (CRP, Cytokine) were reduced after 1 month. Periodontal treatment also reduced HbA1c significantly. Conclusion: Diode laser as an adjunct to non-surgical periodontal therapy have effected significantly to clinical parameters, HbA1c and also reduced systemic inflammation.