Độ nhạy và độ đặc hiệu của một số test tâm sinh lý trong phát hiện sớm nguy cơ nhiễm độc chì của trẻ

Abstract

Objective: To find out the sensitivity and specificity of some psycho-physiological tests in children (age 3-14) with blood lead ≥ 5μg/dL and blood lead < 5μg/dL. Subject and method: 1154 children (from 3 - 14 years old) were taken blood to test blood lead levels by ICP-MS method and to evaluate the intellectual capacity (Raven test, LPS3), reaction time test (simple visual - motor reaction time, simple audio - motor reaction time), memory test (pictures, numbers, words), behaviour test (DBC-P, Vanderbilt), physical index (BMI, Pignet) (depending on age); calculate the sensitivity and specificity of these test. Result: Tests with sensitivity ≥ 57.0% in children with blood lead ≥ 5μg/dL were: DBC-P test, Vanderbilt scale, simple visual - motor reaction time, simple audio - motor reaction time. Tests with specificity ≥ 67.6% in children with blood lead ≥ 5μg/dL were: BMI, Pignet, LPS3 test, Raven test, speech memory test, triangular memory test, animal memory test, number memory test. Conclusion: Some psycho-physiological tests may be of value in the early diagnosis of lead poisoning risk in children, requiring further in-depth research.