Efficacy and safety of 532-nm Q-switched Nd:YAG laser and 755-nm long pulse alexandrite laser in the treatment of solar lentigies
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Abstract
Objective: To evaluate the efficacy and safety as well as comparison between two kinds of laser in the treatment of solar lentigines. Subject and method: 35 solar lentigines were enrolled in this study, in which 22 used QS Nd:YAG 532nm and 13 used long pulse alexandrite 755nm. Each solar lentigo was received one to three session of treatment. Von-Luschan and Mexameter score were measured to evaluate the efficacy of treatment. Side effect was also noted for safety evaluation. Result: For QS Nd: YAG 532nm, Von-Luschan score and Mexameter score statistically decreased after treatment. For long pulse alexandrite, Von-Luschan score after treatment was also significantly lower than before treatment. Hyperpigmentation was note in one case using QS Nd:YAG 532nm (7.7%), erythema was showed in one case and hyperpigmentation in another case using alexandrite 755nm (9.1%). Pain score was significantly lower in patients who treated by QS Nd:YAG 532nm comparing to alexandrite 755nm. Von-Luschan evaluation after first treatment showed statistically different between two kinds of laser. Conclusion: Both QS Nd:YAG 532nm and long pulse alexandrite 755nm show efficacy and safety in the treatment of solar lentigines. QS Nd:YAG 532nm is less painful when comparing to long pulse alexandrite 755nm. QS Nd:YAG 532nm also gained earlier improvement, however, after three treatment sessions, the efficacy of two kinds of laser are similar
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References
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