Mucosal admittance in patients with reflux erosive esophagitis

  • Hang Dao Viet Hanoi Medical University
  • Thanh Nguyen Pham Tuan Hanoi Medical University

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Keywords

: Gastroesophageal reflux disease, mucosal admittance, TCM (Tissue Conductance Meter)

Abstract

Objective: To describe and compare mucosal admittance (MA) in patients with reflux esosive esophagitis (EE) and healthy controls. Subject and method: A cross-sectional descriptive study was conducted from 3/2020 to 6/2020 among patients who had EE on endoscopy compared to healthy controls who went for medical checkup and did not have EE. Result: The study recruited 58 patients (34 with EE and 24 without EE). The mean age was 37.4 ± 8.6 (years), the most common clinical symptoms were epigastric pain (29.3%), regurgitation (15.5%), and heartburn (8.6%). The numbers (percentage) of patients without EE, EE grade A, and B esophagitis were 24 (41.4%), 32 (55.2%), and 2 (3.4%), respectively. The median MA at 5cm and 15cm above Z line (squamocolumnar junction) were 9.7 and 47.4, respectively. The MA in patients with EE was significantly higher than that at health controls at both positions (p<0.001). However, there was no significant difference in both positions between 2 groups with GERD Q score ≥ 8 and GERD Q score < 8 (p>0.05). Conclusion: Mucosal admittance was higher in patients with esophagitis than healthy control.

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References

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