Assessment of clinical, laboratory characteristics and some related factors of recurrent in patient with transverse myelitis
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Abstract
Summary
Objective: To describe the clinical and laboratory characteristics, some prognosis factors of patients with transverse myelitis. Subject and method: A retrospective descriptive study of 25 patients with Neurology Department of 108 Military Central Hospital from January, 2014 to May, 2019. Result: The average age of patients was 44.8 ± 13.4 years old with the percentage of women was 52% and the duration of the plateau phase of symptoms under 2 weeks was 60%. The percentage of the lesion in the thoracic spinal cord was 61.9%, the lesion which was up to the medullary was 14.3% and the lesion which was longer than 2 vertebral segments was 90.5%. The changes in the cerebrospinal fluid (CSF) was seen in 88% of patients with 44% increase in the number of blood cells, 56% increase in the protein level and 68% with positive Pandy’s reaction. In the following-up time of average 34 months, there was 59% of recurrence. Patients with these factors including elevated CSF protein level, the lesion longer than 2 vertebral segments were at higher risk of recurrence. Patients with recurrence had worse functional status (mRs: 3.0 ± 1,9 vs 1.67 ± 1.0, p<0.01). Conclusion: Patients with the lesion longer than 2 vertebral segments and elevated CSF protein level were at higher risk of recurrence. Patients with recurrence had worse functional status.
Keywords: Transverse myelitis, recurrence.
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References
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