Clinical, bacterial classification and resistance rate in patients cholangitis with septic complications

  • Quynh Nguyen Xuan 108 Millitary Central Hospital
  • Trung Vu Thanh 108 Millitary Central Hospital
  • Tuyet Tran Thi Anh 108 Millitary Central Hospital
  • Thang Duong Minh 108 Millitary Central Hospital

Main Article Content

Keywords

Biliary tract infections (BTIs), sepsis

Abstract

Objective: To determine clinical features, classify bacteria and drug resistance rates in patients with cholangitis with complications of sepsis. Subject and method: A prospective and retrospective study in 110 patients with cholangitis with complications of sepsis. All patients were given blood transplants, identified bacteria and susceptibility of antibiotic at the Department of Microbiology - 108 Military Central Hospital, from March 2015 to November 2019. Result: From February 2015 to November 2019, 110 patients were identified with sepsis due to cholangitis. The mean age was 63.2 ± 15.9. Number of patients > 65 years old was 63/110 (55.3%). Men (58.8%) and women (37.7%). Causes of cholangitis: Gallstones (55.3%), cancer of the bile ducts (39.5%), benign stenosis (1.8%). Bacteria classification: Gram-negative infections: 110/110 (100%), in which: E. coli (60.5%), and K. pneumoniae (19.3%). There were 4 types of antibiotics sensitive to bacteria (susceptibility over 80%) including: Ertapenem, imipenem, meropenem and amikacin. Conclusion: The percentage of patients infected with sepsis caused by gram-negative bacteria accounted for 100%, in which E. coli (60.5%), K. pneumoniae (19.3%). Antibiotics effective in treating patients with cholangitis with complications of sepsis include: Ertapenem, imipenem, meropenem and amikacin.

Article Details

References

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Published
Dec 1, 2020
Issue
Volume 15 - No 6/2020
Section
Articles
How to Cite
Nguyen XuanQ., Vu ThanhT., Tran Thi AnhT., & Duong MinhT. (2020). Clinical, bacterial classification and resistance rate in patients cholangitis with septic complications. Tạp Chí Y Dược lâm sàng 108, 15(6), 28-32. Retrieved from https://tcydls108.benhvien108.vn/index.php/YDLS/article/view/630