Prognostic value of global longitudinal strain in patients with septic shock
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Abstract
Objective: We sought to evaluate prognostic value of global longitudinal strain (GLS) by speckle tracking echocardiography in patients with septic shock. Subject and method: This is a prospective, observational study on 90 septic shock patients according to criteria of SCCM/ESICM (2016). This study was perfomed at 108 Military Central Hospital from June 2017 to December 2018. Transthoracic echocardiography and speckle tracking echocardiography were performed on all patients within 24 hours of diagnostic onset. Result: Global longitudinal strain in nonsurvivors was significant greater than survivors (-13.1 ± 3.2% vs -15.8 ± 2.9%, p<0.01). GLS had a very fair diagnostic value for septic shock with AUC 0.76 (p<0.001), at cut-off value -14.2%, sensitivity 66.7% and specificity 84.3%. Conclusion: GLS might be a reliable prognostic predictor of the outcomes of patients with septic shock.
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References
2. Chang WT, Lee WH, Lee WT et al (2015) Left ventricular global longitudinal strain is independently associated with mortality in septic shock patients. Intensive Care Med 41(10): 1791-1799.
3. Hassanin H, Sherif H, Al Hossainy R et al (2018) Left-ventricular global longitudinal systolic strain and strain rate can predict sepsis outcome: comparison between speckle - tracking echocardiography and tissue Doppler imaging. Research and Opinion in Anesthesia and Intensive Care 5(3): 178-186.
4. Innocenti F, Palmieri V, Guzzo A et al (2018) SOFA score and left ventricular systolic function as predictors of short-term outcome in patients with sepsis. Internal and Emergency Medicine 13(1): 51-58.
5. Juan P, Nilda B, Marcelo U (2017) Prognostic value of ventricular function assessed by speckle tracking echocardiography in patients with sepsis. Insuficiencia cardiaca 12(1): 2-8.
6. Kalam K, Otahal P, Marwick TH (2014) Prognostic implications of global LV dysfunction: A systematic review and meta-analysis of global longitudinal strain and ejection fraction. Heart 100 (21): 1673-1680.
7. Orde SR, Pulido JN, Masaki M et al (2014) Outcome prediction in sepsis: Speckle tracking echocardiography based assessment of myocardial function. Crit Care 18(4): 149.
8. Palmieri V, Innocenti F, Guzzo A et al (2015) Left ventricular systolic longitudinal function as predictor of outcome in patients With sepsis. Circ Cardiovasc Imaging 8(11): 003865, discussion 003865.
9. Singer M, Deutschman CS, Seymour CW et al (2016) The third international consensus definitions for sepsis and septic shock (Sepsis-3). Jama 315(8): 801-810.
10. Sturgess DJ, Marwick TH, Joyce C et al (2010) Prediction of hospital outcome in septic shock: A prospective comparison of tissue Doppler and cardiac biomarkers. Crit Care 14(2): 44.
11. Yingchoncharoen T, Agarwal S, Popovic ZB et al (2013) Normal ranges of left ventricular strain: A meta-analysis. J Am Soc Echocardiogr 26(2): 185-191.