Assessment of safety and amelioration of locomotion of bee venom acupuncture on rat model of disc degeneration
Main Article Content
Keywords
Rat model of degenerative spine, amelioration of locomotor, bee venom acupunctures
Abstract
Objective: To investigate effects of the bee venom acupuncture to amelioration of locomotor in rat model of degenerative spine. Subject and method: Comparing motion ranges of hip joints, locomotion abilities and coordination of locomotion of rats before and after bee venom acupunctures. Result: After treatments, motion ranges of hip joints decreased significantly while motion velocities and distance travels in the open field test and riding time in rotarod test increased sigficantly compared to before treatments. Conclusion: Bee venom acupunctures induced amelioration of locomotor in rat model of degenerative spine.
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References
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2. Henry DA (1988) Side-effects of non-steroidal anti-inflammatory drugs. Baillieres Clin Rheumatol 2(2): 425-54.
3. Sok Cheon Pak (2017) Chemical composition of bee venom. Bee Products - Chemical and Biological Properties: 279-285.
4. Lee KH, Yu J, Sun S and Kwon K (2015) Intravenous single dose toxicity of sweet bee venom in sprague-dawley rats. J Pharmacopuncture 18(3): 49-56.
5. Kim JS, Ahmadinia K, Li X et al (2015) Development of an experimental animal model for lower back pain by percutaneous injury-induced lumbar facet joint osteoarthritis. J Cell Physiol 230(11): 2837-2847.
6. Tatem KS, Quinn JL, Phadke A et al (2014) Behavioral and locomotor measurements using an open field activity monitoring system for skeletal muscle diseases. J Vis Exp 91: 51785.
7. Carter RJ, Morton J, Dunnett SB (2001) Motor coordination and balance in rodents. Curr Protoc Neurosci 8: 8-12.