ISSN: 1859 - 2872
Relationships between some apolipoproteins and atherosclerosis condition of cerebral infarction patients
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Abstract
Summary
Objective: To study the relationships between concentrations of apolipoprotein A-I, apolipoprotein B, apolipoprotein B/apolipoprotein A-I ratio and cerebral artery stenosis, occlusion of patients with atherosclerotic cerebral infarction. Subject and method: 146 patients with atherosclerotic cerebral infarction were examined and treated at 108 Military Central Hospital from 10/2017 - 12/2019. Patients were examined clinically, diagnosed with imaging and tested apoA-I, apoB, apoB/apoA-I ratio on admission. Result: The apoA-I concentration of patients with one site stenosis, occlusion (1.32 ± 0.23g/l) were higher than that of patients with multiple sites stenosis, occlusion (1.22 ± 0.22g/l) with p<0.01. The apoB concentration, the apoB/apoA-I ratio of patients with one site stenosis, occlusion (1.26 ± 0.29g/l, 0.99 ± 0.32) were lower than that of patients with multiple sites stenosis, occlusion (1.37 ± 0.30g/l, 1.17 ± 0.34) with p<0.05 and p<0.01. The apoA-I concentration was inversely correlated with the degree of stenosis and occlusion (r = -0.297, p=0.001). The apoB concentration, the apoB/apoA-I ratio were inversely correlated (r = 0.290, p=0.001 and r = 0.343, p=0.001) with the degree of cerebral artery stenosis, occlusion. Conclusion: There was a relationship between apoA-I concentration, apoB concentration, apoB/apoA-I ratio and cerebral artery stenosis, occlusion of patients with atherosclerotic cerebral infarction.
Keywords: Cerebral infarction, apoA-I, apoB, atherosclerosis.
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References
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