The study of related factors and clinical characteristics of generalized pustular psoriasis
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Abstract
Summary
Objective: To analyse some related factors and clinical characteristics of generalized pustular psoriasis. Subject and method: 49 patients with generalized pustular psoriasis treated at the Central Dermatology Hospital, a descriptive cross-sectional study. Result: Male/female ratio: 1/1, mean age of onset: 32.82 ± 19.25 years (the group of under 40-year-old: 67.3%), family history of psoriasis: 14.3%, secondary type: 63.6%. Onset factors: Corticosteroid usage: 30.6%, unknown traditional medicine usage: 24.5%. Conclusion: Pustular psoriasis occurs equally in both genders with late-onset of age which is primary or secondary after a worsening of the plaque psoriasis following an improper treatment. Patients with generalized pustular psoriasis often have severe symptoms including: Fever, fatigue and chills. The certain clinical characteristics are erythema and pustules.
Keywords: Pustular psoriasis, generalized pustular psoriasis.
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References
2. Ohkawara A, Yasuda H et al (1996) Generalized pustular psoriasis in Japan: Two distinct groups formed by differences in symptoms and genetic background. Acta Derm Venereol 76(1): 68-71.
3. Choon SE, Lai NM et al (2014) Clinical profile, morbidity, and outcome of adult-onset generalized pustular psoriasis: Analysis of 102 cases seen in a tertiary hospital in Johor, Malaysia. Int J Dermatol 53(6): 676-684.
4. Baker H and Ryan TJ (1968) Generalised pustular psoriasis: A clinical and epidemiological study of 104 cases. Br J Dermatol 80: 771-793.
5. Fujita H, Terui T et al (2018) Japanese guidelines for the management and treatment of generalized pustular psoriasis: The new pathogenesis and treatment of GPP. J Dermatol 45(11): 1235-1270.
6. Iizuka H, Takahash H, and Yamamoto AI (2003) Pathophysiology of generalized pustular psoriasis. Archives of Dermatological Research 295: 55-59.
7. Borges-Costa Jo, Silva R, and Gonçalves L (2011) Clinical and laboratory features in acute generalized pustular psoriasis: A retrospective study of 34 patients. Am J Clin Dermatol 12(4): 271-276.
8. Hoegler KM, John AM et al (2018) Generalized pustular psoriasis: A review and update on treatment. Journal of the European Academy of Dermatology and Venereology 32(10): 1645-1651.
9. Viguier M, Allez M et al (2004) High frequency of cholestasis in generalized pustular psoriasis: Evidence for neutrophilic involvement of the biliary tract. Hepatology 40(2): 152-458.
10. Tay YK and Tham SN (1997) The profile and outcome of pustular psoriasis in Singapore: A report of 28 cases. Int J Dermatol 36(4): 266-271.