ISSN: 1859 - 2872
Clinical and subclinical characteristics of allergic rhinitis caused by cotton dust allergen of workers in two military garment factories
Main Article Content
Keywords
Abstract
Summary
Objective: To describe clinical and subclinical aspects of allergic rhinitis caused by cotton dust allergen of workers in two military garment factories. Subject and method: A cross-sectional description study on 1812 workers of two military garment factories. Discovering allergy history based on Sample 25b of WHO, classifying functional symptoms and body level by Total Nasal Symptom Score (TNSS). Perform skin prick test, determine the total serum IgE and IgA concentration of the patients. Result: 10.76% of workers exposed to cotton dust suffer from allergic rhinitis. These patients had 4 main functional symptoms: Itchy nose (42.6% moderate and 47.2% mild), sneezing (33.8% moderate and 36.4% slight); runny nose (39.0% moderate and 47.7% mild); nasal congestion (50.3% moderate and 27.7% mild). The majority of patients with allergic rhinitis due to cotton dust suffer from nasal mucosa inflammation (48.1% severe and 28.8% moderate). 70% of patients had inferior turbinate hypertrophy (53.3% mild and 21% moderate). All patients take skin prick testing with positive results, mostly at level 2 (+) and 3 (+). The total serum IgE concentration of patients was high, median 1227.756UI/mL (575.424UI/mL - 38008.333UI/mL). On the contrary, the patient's total serum IgA level was low, median 61.509mg/dL (26.773mg/dL - 211.826mg/dL). Conclusion: Patients with allergic rhinitis caused by cotton dust allergen have symptoms similar to those with this disease in general. Most patients have 4 functional symptoms, 2 symptoms of nasal mucosa and inferior turbinate, all with positive skin prick test (+) and high level of IgE, low level of IgA.
Keywords: Allergic rhinitis, cotton dust, military garment factory.
Article Details
References
2. Ngô Thanh Bình (2011) Nghiên cứu đặc điểm lâm sàng, cận lâm sàng và hiệu quả điều trị miễn dịch đặc hiệu đường dưới lưỡi ở bệnh nhân viêm mũi dị ứng do dị nguyên lông vũ. Trường Đại học Y Hà Nội.
3. Vũ Trung Kiên (2013) Thực trạng viêm mũi dị ứng của học sinh trung học cơ sở thành phố Thái Bình, Hải Phòng và hiệu quả điều trị miễn dịch đặc hiệu bằng dị nguyên Dermatophagoides pteronyssinus. Trường Đại học Y Thái Bình.
4. Vũ Văn Sản (2002) Nghiên cứu những đặc điểm lâm sàng của bệnh viêm mũi dị ứng nghề nghiệp do bụi bông - len ở Công ty Dệt thảm Hải Phòng. Học viện Quân y.
5. Badrossadat R, Hazhirkarzar B, Seyyed HG (2013) Serum level of immunoglobulins in patients with respiratory allergic diseases, Front. Immunol. Conference Abstract: 15th International Congress of Immunology (ICI).
6. Daniel Chung, KT Park, Bharat Yarlagadda et al (2014) The significance of serum total immunoglobulin E for in vitro diagnosis of allergic rhinitis. in International forum of allergy & rhinology. Wiley Online Library.
7. Wilson DR, Torres Lima M, Durham SR (2005) Sublingual immunotherapy for allergic rhinitis: Systematic review and meta-analysis*. Allergy 60(1): 4-12.
8. Francesco D, Schumann G, Thomas L et al (1996) Consensus of a group of professional societies and diagnostic companies on guidelines for interim reference ranges for 14 proteins in serum based on the standardization against the IFCC/BCR/CAP reference material (CRM 470). European Journal of Clinical Chemistry and Clinical Biochemistry 34(6): 517-520.
9. Philippe JB, Pascal D, Philippe D et al (2013) Impact of allergic rhinitis symptoms on quality of life in primary care. International archives of allergy and immunology 160(4): 393-400.
10. Rifat K, Evrim B, Lokman U et al (2013) Correlation of symptoms with total IgE and specific IgE levels in patients presenting with allergic rhinitis. Therapeutic advances in respiratory disease 7(2): 75-79.
Article Sidebar
