ISSN: 1859 - 2872
Relationship between bone mineral density and fracture risk with some clinical and subclinical characteristics in type 2 diabetic patients
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Abstract
Summary
Objective: Study on the relationship between bone mineral density and fracture risk with some clinical and subclinical characteristics in patients with type 2 diabetes treated at 175 Military Hospital. Subject and method: A cross-sectional descriptive study. 101 patients with type 2 diabetes were treated at Cardiology-Rheumatology-Endocrinology Department of 175 Military Hospital from April 2018 to March 2019. Result: The average value of lumbar spine bone mineral density as well as femoral neck was inversely correlated significantly with the time of detection of type 2 diabetes (r = -0.52 and -0.572, p<0.05). The femoral neck bone density had a significant inverse correlation with age (r = -0.282, p<0.05), and had a significant positive correlation with height and weight (r = 0.52, 0.475 respectively; p<0.05). Bone mineral density of the lumbar spine has a significant positive correlation with height, weight and BMI (r = 0.349, 0.547, 0.364 respectively; p<0.05). The proportion of patients at high risk of fractures in the next 10 years according to FRAX model were 13.9%. The probability of femoral neck fracture as well as general fracture probability were positively correlated with duration of diabetes with r = 0.566 and 0.54 respectively; p<0.05. Conclusion: The bone mineral density of the lumbar spine was negatively correlated with the time of detecting type 2 diabetes, and was positively correlated with height, weight and BMI. The bone density of the femoral neck was negatively correlated with age and time of disease detection, positively correlated with height and weight. Probability of femoral neck fracture and general fracture probability were positively correlated with duration of type 2 diabetes.
Keywords: Bone mineral density, fracture risk, type 2 diabetes, FRAX model.
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References
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