ISSN: 1859 - 2872
Short-term outcomes of anatomical laparoscopic liver resection using indocyanine green fluorescence imaging for hepatocellular carcinoma
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Abstract
Objective: To evaluate the short-term outcomes and safety of indocyanine green (ICG)-guided laparoscopic anatomical liver resection for hepatocellular carcinoma (HCC). Subject and method: A prospective, single-arm interventional study was conducted in patients with HCC who underwent ICG-guided laparoscopic anatomical liver resection at 108 Military Central Hospital from December 2024 to December 2025. Result: A total of 50 patients were included, with a mean age of 59.2 ± 10 years; 88% were male. All patients had preserved liver function (Child–Pugh A). R0 resection was achieved in 100% of cases, with a mean surgical margin of 10 ± 11mm. The overall postoperative complication rate was 16%, predominantly minor complications (Clavien–Dindo grade I–II). Specific complications included bile leakage (6.0%), ascites (4.0%), postoperative bleeding (2.0%), pleural effusion (2.0%), and sepsis (2.0%). The mean hospital stay was 8.1 ± 2.2 days. No reoperation, readmission, or 30-day mortality was observed. Conclusions: ICG-guided laparoscopic anatomical liver resection for HCC is a safe and feasible approach with favorable short-term outcomes. The use of ICG fluorescence enhances intraoperative anatomical orientation, facilitates precise parenchymal transection, and contributes to achieving adequate surgical margins while preserving functional liver parenchyma.
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References
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