Assessment of transcranial doppler ultrasonographic changes in patients with elevated intracranial pressure secondary to acute intracerebral hemorrhage
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Abstract
To evaluate changes in selected transcranial Doppler (TCD) parameters of the middle cerebral artery in patients with acute intracerebral hemorrhage associated with elevated intracranial pressure and/ severe clinical conditions. Subject and method: The study included 42 patients with acute intracerebral hemorrhage, with a total of 274 bilateral middle cerebral artery TCD examinations, conducted at the Institute of Neurology, 108 Military Central Hospital. Result: No statistically significant differences were observed between the TCD parameters of the bilateral middle cerebral arteries. During coma (Glasgow Coma Scale ≤ 8) or in patients with early mortality, the pulsatility index (PI) tended to increase; however, this difference was not statistically significant (p>0.05). Patients with elevated intracranial pressure (≥ 20 mmHg) demonstrated significantly higher PI values (right/left: 1.83 ± 0.63/1.87 ± 0.67) and lower end-diastolic flow velocity (FVD) (right/left: 13.59 ± 13.8/13.96 ± 14.14cm/s) compared with those with normal intracranial pressure (< 20mmHg) (PI right/left: 1.33 ± 0.59/1.36 ± 0.59; FVD right/left: 20.66 ± 14.06/19.25 ± 12.45cm/s), with p<0.05. In contrast, systolic flow velocity (FVS) and mean flow velocity (FVM) did not differ significantly between the two groups. Conclusion: Middle cerebral artery transcranial Doppler in patients with acute intracerebral hemorrhage and elevated intracranial pressure shows characteristic changes, including increased pulsatility index and decreased end-diastolic flow velocity. Monitoring these parameters may help track trends of intracranial pressure elevation at the bedside.
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