ISSN: 1859 - 2872
Treatment outcomes of solar lentigines using q-switched Nd:YAG 532-NM LASER
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Abstract
To evaluate the therapeutic outcomes of age spot treatment using a 532-nm Q-switched Nd:YAG laser with artificial intelligence–assisted lesion analysis combined with an intelligent cooling system. Subject and method: twenty-six patients with Fitzpatrick skin types III and IV, presenting with 89 facial lesions diagnosed as age spots, were enrolled and treated at the Aesthetic Center, 108 Military Central Hospital. All lesions were treated in a single session using a Reepot Q-switched 532-nm Nd:YAG laser with a 4-mm spot size, 1-Hz, and energy settings of 200–220 mJ, in combination with an AI-based lesion recognition system and an intelligent skin-cooling technology. Immediately after treatment, the treated areas were covered with a shaped silicone dressing. Treatment outcomes were independently assessed by five dermatologists based on standardized photographs using a 5-grade improvement scale at the time of crust detachment, and at 1 and 3 months post-treatment; Patient pain and satisfaction scores (Numeric rating Scale NRS 0-10; VAS 0-10) during laser treatment. Result: At 12 weeks after a single treatment session, 23 patients (88.46%) achieved excellent pigment improvement (Grade 5), while 3 patients (11.54%) showed good improvement (Grade 3). Procedural pain was minimal, with a mean NRS score of 1.8 ± 0.9, and patient satisfaction was high, with a mean VAS score of 8.9 ± 1.0. Post-inflammatory hyperpigmentation was observed in one patient (3.85%). Conclusion: Artificial intelligence - assisted lesion analysis combined with operative epidermal cooling using a 532-nm Q-switched laser demonstrates promising therapeutic efficacy while minimizing adverse effects in the treatment of age spots among Vietnamese patients.
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References
2. Kang HJ et al (2017) Postinflammatory hyperpigmentation associated with treatment of solar lentigines using a Q-Switched 532-nm Nd: YAG laser: A multicenter survey. J Dermatolog Treat 28(5): 447-451.
3. Wang CC et al (2006) A comparison of Q-switched alexandrite laser and intense pulsed light for the treatment of freckles and lentigines in Asian persons: A randomized, physician-blinded, split-face comparative trial. J Am Acad Dermatol 54(5): 804-810.
4. Wanner M et al (2016) Immediate skin responses to laser and light treatments: Therapeutic endpoints: How to obtain efficacy. Journal of the American Academy of Dermatology 74(5): 821-833.
5. Davis EC, Callender VD (2010) Postinflammatory hyperpigmentation: a review of the epidemiology, clinical features, and treatment options in skin of color. J Clin Aesthet Dermatol 3(7): 20-31 PMID: 20725554; PMCID: PMC2921758.
6. Lacz NL et al (2004) Postinflammatory hyperpigmentation: A common but troubling condition. Int J Dermatol 43(5): 362-365.
7. Kim YH et al (2023) The efficacy and stability of 532 nm nanosecond Nd: YAG Vasculature Salvage Laser Surgery (VSLS) system in ex vivo pigmented micropig skin. Lasers Med Sci 38(1): 180.
8. Chan MWM et al (2019) A Prospective Study in the Treatment of Lentigines in Asian Skin Using 532 nm Picosecond Nd:YAG Laser. Lasers Surg Med 51(9): 767-773.
9. Negishi K et al (2013) Comparative study of treatment efficacy and the incidence of post-inflammatory hyperpigmentation with different degrees of irradiation using two different quality-switched lasers for removing solar lentigines on Asian skin. J Eur Acad Dermatol Venereol 27(3): 307-12.
10. Negishi K, Akita H, and Matsunaga Y (2018) Prospective study of removing solar lentigines in Asians using a novel dual-wavelength and dual-pulse width picosecond laser. Lasers Surg Med 50(8): 851-858.
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