Invasive aspergillosis after liver transplantation: A rare case of multisystem involvement and successful treatment
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Tóm tắt
Background: Aspergillosis is a rare but severe opportunistic fungal infection in liver transplant patients. Early and definitive diagnosis is crucial for selecting antifungal therapy and adjusting immunosuppressive regimens to improve patient outcomes. Case report: A 46-year-old male, three months post-liver transplant, was hospitalized with fever, neutropenia, left hemiparesis, leg pain, and skin lesions. CT angiography revealed partial femoral and calf artery occlusion, while brain MRI suggested invasive fungal infection. Skin biopsy confirmed Aspergillus infection. The patient was treated with voriconazole and tacrolimus, leading to significant improvement. After one month of antifungal therapy, he achieved stable liver function and was discharged. This case highlighted the importance of early diagnosis and appropriate treatment in managing Aspergillus infections.
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