ISSN: 1859 - 2872
Characteristics of left ventricular longitudinal stress index on ultrasound mechanical tissue markers in patients with chronic heart failure at Viet Tiep Friendship Hospital
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Abstract
Objective: To investigate the left ventricular global longitudinal strain (GLS) and its correlation with left ventricular ejection fraction (LVEF% - Biplane) in patients with chronic heart failure. Subject and method: This was a prospective, descriptive study conducted on 88 patients diagnosed with chronic heart failure who were hospitalized at the Department of Cardiology, Viet Tiep Friendship Hospital, from January 2024 to September 2024. All patients were followed for cardiovascular events over a 5-month period after their first admission. Clinical history, physical examination, biochemical testing, and echocardiographic assessment were performed, including measurement of left ventricular ejection fraction (LVEF%) and global longitudinal strain (GLS) following standardized protocols. The rates of rehospitalization and cardiovascular events were recorded. Result: The mean GLS was -13.25 ± 6.17. In subgroup analysis: reduced EF% group, -8.59 ± 3.36; mildly reduced EF% group, -11.50 ± 2.31; preserved EF% group, -19.63 ± 3.73. According to NYHA classification: NYHA II, -19.63 ± 3.73; NYHA III, -9.71 ± 3.24; NYHA IV, -6.03 ± 2.39. A strong negative linear correlation was observed between GLS and LVEF (r = -0.88; p < 0.01). Statistically significant differences in GLS were found between patients with and without hypertension, type 2 diabetes mellitus, and chronic kidney disease (-11.94 ± 5.14 vs. -15.05 ± 7.04; p = 0.02; -11.42 ± 5.83 vs. -14.34 ± 6.16; p = 0.03; -11.25 ± 5.49 vs. -15.88 ± 6.10; p = 0.01, respectively). The average length of hospital stay was longer in the low GLS group (5.11 ± 0.65 days) compared with the high GLS group (3.23 ± 0.60 days, p = 0.03). Conclusion: The mean left ventricular global longitudinal strain in patients with chronic heart failure was reduced and showed a strong inverse correlation with left ventricular ejection fraction. Lower GLS values were observed in patients with reduced EF%, higher NYHA functional class, and those with comorbid hypertension, type 2 diabetes mellitus, or chronic kidney disease. Patients with lower GLS had longer hospital stays compared to those with normal GLS.
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References
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