Phân tích thực trạng sử dụng thuốc trong điều trị đái tháo đường típ 2 tại Bệnh viện Thanh Nhàn 2024

Abstract

Objective: To analyze the current status of medication use in the treatment of type 2 diabetes mellitus (T2DM) at Thanh Nhan Hospital. Subject and method: A retrospective, non-interventional study was conducted based on outpatient prescription and medical record data. The study population included patients with T2DM who had monthly follow-up visits between January 1, 2024, and December 31, 2024. A systematic sampling method was employed, with an optimized sample size (n = 396). Result: The mean age of participants was 67.8 ± 10.0 years. The proportion of patients classified as having very high cardiovascular risk was 62.4%. Insulin-based regimens (58.8%) were more common than oral-only regimens (41.2%). Among patients with HbA1c ≥ 8.5%, 18.2% of oral therapy regimens and 38.8% of insulin-containing regimens were not appropriately intensified. The prescription rate of SGLT2 inhibitors among eligible patients remained suboptimal: in those with concomitant heart failure, 69.2% received the drug at least once, and 7.7% were prescribed it continuously. For antihypertensive therapy, angiotensin II receptor blockers (ARBs) were most frequently used (59.7%), followed by diuretics (56.1%); the most common regimen was the ARB + diuretic combination (30.9%). Regarding lipid-lowering therapy, the proportion of patients at high and very high cardiovascular risk receiving high-intensity statins was 7.1% and 9.7%, respectively. Conclusion: Antidiabetic treatment regimens should be more appropriately adjusted according to HbA1c levels, particularly in patients who have not achieved glycemic targets. The use of high-intensity statins should be enhanced to prevent cardiovascular complications.