ISSN: 1859 - 2872
Prognostic value of optic nerve sheath diameter by ultrasound in predicting sepsis-associated encephalopathy
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Abstract
Objective: To evaluate the prognostic value of ultrasound-measured ONSD in predicting brain dysfunction in patients with sepsis. Subject and method: A cross-sectional descriptive study was conducted on 70 patients aged ≥ 18 years who were diagnosed with sepsis according to the 2016 SCCM/ESICM consensus. ONSD was measured by ultrasound within the first 24 hours of hospital admission. Brain dysfunction was assessed using the CAM-ICU criteria and/or a Glasgow Coma Scale score < 15. Result: SAE occurred in 54.3% of septic patients. The mean ONSD value in the SAE group was significantly higher than that in the non-SAE group (5.7 ± 0.4mm vs. 4.9 ± 0.3mm, p<0.05). ONSD showed predictive value for SAE with an AUC of 0.95; at a cutoff of ONSD ≥ 5.3mm, the sensitivity was 84% and specificity was 93%. Both SOFA score and ONSD were independent factors associated with SAE. Conclusion: Ultrasound measurement of ONSD is a feasible, non-invasive, and valuable tool for predicting brain dysfunction in patients with sepsis.
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References
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