ISSN: 1859 - 2872
Association between changes in rectus femoris cross-sectional area measured by ultrasound and mechanical ventilation status in patients with septic shock
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Abstract
Objective: To evaluate the association between changes in rectus femoris cross-sectional area (CSA) and mechanical ventilation status and duration in patients with septic shock. Subject and method: A prospective descriptive study was conducted on 116 patients with septic shock at 108 Military Central Hospital. Rectus femoris CSA was measured by bedside ultrasound at admission (T0), day 4 (T4), and day 7 (T7). Result: Among the 116 patients, 93 (80.2%) required mechanical ventilation. The absolute change in rectus femoris CSA at days 4 and 7 was significantly greater in the ventilated group compared to the non-ventilated group (day 4: -0.24cm² vs. -0.16cm², p<0.01; day 7: -0.38cm² vs. -0.23cm², p<0.01). The percentage reduction in CSA was also significantly higher in the ventilated group (day 4: -9.96% vs. -5.57%, p<0.01; day 7: -14.8% vs. -8.52%, p<0.01). ROC analysis demonstrated that the absolute CSA change at day 7 (ΔCSA7) could distinguish prolonged mechanical ventilation (> 7 days) with an area under the curve (AUC) of 0.676 (95% CI: 0.560 - 0.792), sensitivity of 75%, and specificity of 62% at the cutoff point of -0.355cm². Conclusion: Changes in rectus femoris CSA are associated with mechanical ventilation status and duration in patients with septic shock.
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References
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