Extracorporeal cardiopulmonary resuscitation (ECPR) in refractory cardiac arrest: Organizational experience at a provincial hospital through two clinical cases
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Abstract
Introduction: Refractory cardiac arrest, a state of prolonged circulatory cessation unresponsive to standard advanced life support, presents a formidable clinical challenge with an exceedingly poor prognosis. Extracorporeal cardiopulmonary resuscitation (ECPR) is a potential life-saving solution; however, implementing this technique in provincial centers with limited resources remains challenging. We report our initial experience in developing and applying an optimized ECPR model within the practical context of Vietnam. Case report: We present two clinical cases of in-hospital refractory cardiac arrest with contrasting outcomes. Case 1 involves a 56-year-old male patient with acute myocardial infarction who had a low-flow time (from arrest to ECMO flow) of 60 minutes; the patient regained consciousness but had irreversible heart failure. Case 2 is a 32-year-old female patient with fulminant myocarditis who had a low-flow time of only 10 minutes and achieved a full recovery. These two cases illustrate the role of ECPR as a "bridge to intervention" and a "bridge to recovery," while also emphasizing the importance of system optimization. Conclusion: Successful implementation of ECPR in resource-limited centers is feasible through the development of a well-structured organizational model, multidisciplinary team training, and strict adherence to protocols aimed at minimizing intervention time.
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References
2. Richardson ASC, Tonna JE, Nanjayya V et al (2021) Extracorporeal Cardiopulmonary Resuscitation in Adults. Interim Guideline Consensus Statement From the Extracorporeal Life Support Organization. ASAIO J 67(3): 221-228.
3. Chen YS, Lin JW, Yu HY et al (2008) Cardiopulmonary resuscitation with assisted extracorporeal life-support versus conventional cardiopulmonary resuscitation in adults with in-hospital cardiac arrest: An observational study and propensity analysis. Lancet 372(9638): 554-561.
4. Tsao CW, Aday AW, Almarzooq ZI et al (2022) Heart Disease and Stroke Statistics 2022 Update: A Report From the American Heart Association. Circulation 145(8): 153-639.
5. Meaney PA, Bobrow BJ, Mancini ME et al (2013) Cardiopulmonary resuscitation quality: Improving cardiac resuscitation outcomes both inside and outside the hospital: A consensus statement from the American Heart Association. Circulation 128(4): 417-435.
6. Reynolds JC, Frisch A, Rittenberger JC, Callaway CW (2013) Duration of resuscitation efforts and functional outcome after out-of-hospital cardiac arrest: When should we change to novel therapies? Circulation 128(23): 2488-2494.
7. Richardson ASC, Schmidt M, Bailey M, Pellegrino VA, Rycus PT, Pilcher DV (2017) ECMO Cardio-Pulmonary Resuscitation (ECPR), trends in survival from an international multicentre cohort study over 12-years. Resuscitation 112: 34-40.
8. Wengenmayer T, Tigges E, Staudacher DL (2023) Extracorporeal cardiopulmonary resuscitation in 2023. Intensive Care Med Exp 11(1): 74.
9. Yannopoulos D, Bartos J, Raveendran G et al (2020) Advanced reperfusion strategies for patients with out-of-hospital cardiac arrest and refractory ventricular fibrillation (ARREST): a phase 2, single centre, open-label, randomised controlled trial. Lancet 396(10265): 1807-1816.
10. Belohlavek J, Smalcova J, Rob D et al (2022) Effect of Intra-arrest Transport, Extracorporeal Cardiopulmonary Resuscitation, and Immediate Invasive Assessment and Treatment on Functional Neurologic Outcome in Refractory Out-of-Hospital Cardiac Arrest: A Randomized Clinical Trial. JAMA 327(8): 737-747.
ISSN: 1859 - 2872