ISSN: 1859 - 2872
Assessment of SPARCC scoring and its correlation with clinical and paraclinical parameters in patients with axial spondyloarthritis
Main Article Content
Keywords
Abstract
Objective: To evaluate the SPARCC score and its association with clinical characteristics, laboratory parameters, and disease activity indices in patients with axial spondyloarthritis (axSpA). Subject and method: A cross-sectional descriptive study was conducted on 50 patients diagnosed with axSpA at the 108 Military Central Hospital from September 2023 to April 2025. Clinical features, laboratory data, and sacroiliac joint magnetic resonance imaging (MRI) findings were collected. The SPARCC score was calculated based on the criteria of the Spondyloarthritis Research Consortium of Canada. Result: The mean SPARCC score was 29.28 ± 18.93. Patients with BASDAI ≥ 4 had significantly higher SPARCC scores compared to those with BASDAI < 4 (p<0.05). A weak positive correlation was observed between SPARCC score and ASDAS-CRP (r = 0.29, p=0.04), while a moderate positive correlation was found with BASDAI (r = 0.31, p=0.02). Conclusion: The SPARCC score is a valuable tool in assessing sacroiliitis on MRI in axSpA patients. It shows weak to moderate positive correlations with disease activity indices and may serve as an objective marker to support disease monitoring.
Article Details
References
2. Maksymowych WP (2019) The role of imaging in the diagnosis and management of axial spondyloarthritis. Nature Reviews Rheumatology 15(11): 657-672.
3. Maksymowych WP, Inman RD, Salonen D et al (2005) Spondyloarthritis research Consortium of Canada magnetic resonance imaging index for assessment of sacroiliac joint inflammation in ankylosing spondylitis. Arthritis Care & Research. 53(5): 703-709.
4. Zhang P, Yu K, Guo R et al (2015) Ankylosing spondylitis: correlations between clinical and MRI indices of sacroiliitis activity. Clinical radiology 70(1): 62-66.
5. Singh BK, Tiwari M, & Meena PK (2024) Correlation between Ankylosing Spondylitis Disease Activity Score and MRI Scoring in Patients with Ankylosing Spondylitis: A Cross-sectional Study. Journal of Clinical & Diagnostic Research 18(8).
6. Bùi Hải Bình, Phạm Kim Linh (2024) Đặc điểm bệnh nhân viêm cột sống dính khớp điều trị nội trú tại Trung tâm cơ xương khớp Bệnh viện Bạch Mai năm 2021. Tạp chí Y học Việt Nam, 539, tr. 5-9.
7. Chung HY, Huang JX, Chan SCW, Lee KH, Tsang HHL, Lau CS (2022) Clinical, radiological, and magnetic resonance imaging characteristics of axial spondyloarthritis with late onset. Medicine 101(29): 29523.
8. Inan O, Aytekin E, Dogan YP et al (2024) Correlation between clinical disease activity and sacroiliac magnetic resonance imaging detection in axial spondyloarthropathy. Archives of Rheumatology 39(1): 115.
9. Chung HY, Machado P, van Der Heijde D, d'Agostino M-A, Dougados M (2011) HLA-B27 positive patients differ from HLA-B27 negative patients in clinical presentation and imaging: results from the DESIR cohort of patients with recent onset axial spondyloarthritis. Annals of the rheumatic diseases 70(11): 1930-1936.
10. van Gaalen FA, Rudwaleit M (2023) Challenges in the diagnosis of axial spondyloarthritis. Best Practice & Research Clinical Rheumatology 7(3): 101871.
11. Rudwaleit M, Marzo-Ortega H, Navarro-Compán V, et al (2024) Exploratory analysis of the potential disconnect between objective inflammatory response and clinical response following certolizumab pegol treatment in patients with active axial spondyloarthritis. RMD open 10(3): 004369.
12. Tian H, Li T, Wang Y et al (2023) The correlations between C-reactive protein and MRI-detected inflammation in patients with axial spondyloarthritis: A systematic review and meta-analysis. Clinical Rheumatology 42(9): 2397-2407.
Article Sidebar
