Dengue viral encephalitis: A case series report

  • Đào Hữu Nam Bệnh viện Nhi Trung ương
  • Phạm Ngọc Toàn Bệnh viện Nhi Trung ương
  • Nguyễn Văn Lâm Bệnh viện Nhi Trung ương
  • Đỗ Thị Đài Trang Trường Đại học Y Hà Nội

Main Article Content

Keywords

Dengue hemorrhagic fever, dengue viral encephalitis, children

Abstract

Dengue hemorrhagic fever is a common acute infectious disease caused by the dengue virus with symptoms of fever, hemorrhage and plasma leakage. Neurological complications due to dengue virus are rare and dengue viral encephalitis is the most common among central nervous complications. We reported two cases of female children, aged 14 and 7, both children were diagnosed with dengue hemorrhagic fever and presented with fever, headache, and mental disorders, which are critical indicators of potential neurological involvement. The abnormal cerebrospinal fluid (CSF) findings pointed towards viral encephalitis. Both cases were confirmed diagnosis of dengue viral encephalitis by the presence of dengue IgM antibodies in the CSF. Conclusion: Dengue virus encephalitis is a rare neurological complication. Children with dengue hemorrhagic fever and acute neurological symptoms should be considered for a diagnosis of dengue viral encephalitis and perform tests to look for evidence of dengue virus in the cerebrospinal fluid, and to rule out other encephalitis causes.

Article Details

References

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