Evaluation of experimental uterine removal and transplantation results on dogs at 108 Military Central Hospital

  • Nguyen Thanh Ha 108 Military Central Hospital

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Keywords

Uterus transplantation, experimental study

Abstract

Objective: To evaluate early results of an experimental uterine removal and transplantation in a dog model. Subject and method: A experimental prospective interventional study, was performed on 10 pairs of dogs at 108 Military Central Hospital from January 2020 to October 2020. Result: The average uterine ischemia time was 34.4 ± 4.14 minutes. The average surgical time for hysterectomy and transplantation in recipient dogs was 228 ± 41.85 minutes. The length of the uterine artery in the donor dog was 20 ± 0.13mm. The largest diameter of the uterine artery was 6.5mm, the smallest was 3mm. The average thickness was 0.07 ± 0.01mm. The length of the uterine vein in the donor dog was 30.3 ± 2.4mm, the vein diameter was also larger than the artery, the largest was 9mm, the smallest was 6mm, the vein wall thickness was 0.03 ± 0.01mm. The diameter of the uterus-vaginal anastomosis was 20.02 ± 1.09m, the anastomosis thickness was 7 ± 0.04mm. The diameter of the utero-fallopian tube anastomosis was 10.46 ± 1.2mm. The amount of blood lost during surgery was 456 ± 45ml. The amount of blood transfused during surgery was 470 ± 32ml. During surgery, there were 2 cases of pelvic vein rupture, 1 case of ureteral injury, 9/10 cases had good anastomosis circulation after transplantation, 1 case had complete anastomosis obstruction. The average postoperative survival time was 8.23 ​​± 12 days. After transplantation, there were 3 cases of infection, 2 cases of bleeding at the arteriovenous anastomosis, 1 case of both arterial and venous embolism.

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References

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