Bước đầu nghiên cứu hình ảnh cộng hưởng từ sức căng khuếch tán và tưới máu thận ở người hiến khỏe mạnh trên máy chụp cộng hưởng từ 3.0T

Abstract

Background: Diffusion tensor imaging (DTI) and renal perfusion imaging (Arterial Spin Labelling- ASL) are new imaging methods for kidney diseases without the use of magnetic contrast agents. Imaging research on normal, healthy kidneys is an important basis for future research on kidney diseases. Objective: Study of Diffusion Tensor Imaging (DTI) and Renal Perfusion in Healthy Kidney Donors. Subject and method: This study included 35 patients with 70 healthy donor kidneys, of which 18 were male (mean age: 33.44 ± 8.80 years) and 17 were female (mean age: 31.0 ± 5.37 years). All subjects underwent 3.0 Tesla MRI (GE) in a cross-sectional descriptive study. Result: The average volume of the right kidney among the 35 patients was 92.45 ± 14.96cm³, while the left kidney volume was 89.36 ± 17.48cm³. The average number of cortical medullary rays was 10,736.2 ± 2,033.8 for the right kidney and 11,104.1 ± 2,492.6 for the left kidney. The FA and ADC values of the right donor kidney were 0.43 and 3.06, respectively, while those of the left donor kidney were 0.55 and 3.04. These differences were not statistically significant (p>0.05). RBF index was higher in the cortex compared to the medulla, and it was also greater at the upper and lower poles compared to the mid-region. Conclusion: Research results show that diffusion tensor MRI and unenhanced renal perfusion on currently healthy kidneys help provide images and renal perfusion indices in a group of normal people, thereby providing a useful database for compare and serve as a control group for future studies on kidney diseases.