Kết quả sớm ghép giác mạc xuyên từ người hiến chết não

Abstract

Objective: To describe the early results of penetrating keratoplasty using corneal graft from brain-dead donors. Subject and method: A prospective clinical study of 9 patients (9 eyes) treated with optical penetrating keratoplasty at Department of Ophthalmology - 108 Military Central Hospital between January 2024 and September 2024. The surgical techniques were central corneal drilling, suturing the corneal graft (from a brain-dead donor) with 10-0 nylon interrupt threads and coordination techniques (if necessary). Evaluating the level of vision improvement, graft condition, and complications after surgery for up to 3 months. Result: The patients mean age was 59.3 ± 13.3 with 66.6% of them was male. The percentage of corneal scar after bullous keratopathy was highest (44.4%). 100% of eyes had blind vision (< CF 3m). The mean of corneal preservation time was 2.5 days. The mean size of grafts was 8.0 ± 0.3mm. The average time of epithelial healing was 8.2 ± 10.1 days. Postoperative visual acuity was improved in all eyes and there were not any eyes that had blind vision 3 months after surgery. All of the eyes had clear graft 3 months after surgery. Surgical complications included infiltration at the suture (33.3%), delayed epithelial healing (22.2%) and loose sutures (11.1%). There were not any eyes that had glaucoma, cataract and graft rejection during 3 months of follow-up. Conclusion: Penetrating keratoplasty using corneal donors from brain-dead donors seems to be effective surgery to treat corneal lesions with optical purpose.