ISSN: 1859 - 2872
Is old age a contraindication for Whipple procedure in pancreatic head cancer?
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Abstract
Objective: To evaluate the role of age in pancreaticoduodenectomy due to pancreatic head cancer in relation to the rate of complications and mortality after surgery. Subject and method: 89 patients underwent radical Whipple procedure and standard lymphadenectomy for pancreatic head cancer at Viet Duc University Hospital from January 2013 to August 2020, divided into two groups under 60 and over 60 years old. Result: Albumin were statistically significant between 2 groups (40.0 ± 4.4 and 37.5 ± 4.2) (p<0.009). There was no difference in operation time (367.9 ± 95.4 and 342.3 ± 92.9 minutes); days of hospitalization (13.5 ± 4.2 and 14.8 ± 7.7), 90-day mortality rate (11.1% vs. 1.9%) and 5-year overall survival (p>0.05). In multivariate regression analysis for survival rate after 3 years, factors such as age, gender, and staging showed no correlation. Conclusion: The complications but not the overall survival was different among the 2 groups. The decision of radical resection should be carefully discussed in patients with underlying medical condition.
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References
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