ISSN: 1859 - 2872
Homeostasis model assessment (HOMA) of insulin resistance and related factors in psoriasis patients
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Abstract
Objective: To compare the rate of insulin resistance assessed by the HOMA-IR index in psoriasis patients and control group. Subject and method: A cross-sectional study on 102 psoriasis patients and 51 healthy controls at Ho Chi Minh City Hospital of Dermato-Venereology from February 2023 to August 2023. Psoriasis severity was assessed by BSA and PASI scores. Insulin resistance was assessed by the HOMA-IR index. Result: The HOMA-IR index in the psoriasis patients was higher than that in the control group (p<0.05). The rate of insulin resistance (HOMA-IR ≥ 2.5) in the psoriasis patients was 48%, three times higher than that in the control group (OR = 3, p=0.004). There was a positive, moderate correlation between HOMA-IR and BMI (r = 0.436, p<0.001); positive, weak correlation between HOMA-IR and waist circumference (r = 0.294, p=0.003) in the psoriasis patients. Conclusion: Psoriasis patients had a higher rate of insulin resistance than subjects without psoriasis; HOMA-IR was positively correlated with BMI and waist circumference.
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References
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