ISSN: 1859 - 2872
Survey on the use of amikacin antibiotics at Saint Paul General Hospital (8-9/2023)
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Abstract
Objective: To survey the current status of amikacin use in inpatients at Saint Paul General Hospital. Subject and method: A cross-sectional study was conducted on the medical records of patients aged 18 years and older who used amikacin for at least 1 day from August 1, 2023 to September 30, 2023 at Saint Paul General Hospital. Result: Of the total 294 medical records that met the research criteria, 30.3% of patients were prescribed amikacin in the intensive care units. The proportion of patients prescribed microbiological testing was 17.0%. E. coli was the most common pathogen among the bacterial isolates (41.4%). The majority of patients were prescribed amikacin in the empirical regimen with a rate of 90.5%, and 100% of patients were given amikacin in the combination regimen, mainly beta-lactam combination (87.9%). The median dose of amikacin was 16.7mg/kg/day. Of the 113 patients whose creatinine was monitored during or after amikacin use, 10 patients (8.8%) had acute kidney injury. Conclusion: This study provided information on the current status of amikacin use at Saint Paul General Hospital, thereby providing a basis for developing strategies to manage aminoglycoside antibiotics to ensure effectiveness and safety in patients.
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References
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