Nghiên cứu biểu hiện, giá trị phân biệt của một số đặc điểm lâm sàng, xét nghiệm giữa nhóm sống - tử vong ở bệnh nhân sốt xuất huyết dengue nặng

Abstract

Objective: To determine the manifestations and discriminant validity of some clinical and laboratory test features between survival and death groups in patients with severe dengue hemorrhagic fever. Subject and method: Using comparative description and ROC curve to determine discriminant validity of some clinical and laboratory test features in 68 patients with severe dengue fever at Military Hospital 103. Result: The proportion of patients with underlying diseases, symptoms of consciousness disorder, and shock in the survival group were 34%, 4%, 16%, and that in the death group were 77.8%, 33.3%, 61.1% respectively. The number of white blood cells, neutrophils, creatinine, APTT time, CRP in the death group were higher than that in the survival group. Red blood cell counts, hemoglobin, hematocrit and prothrombin ratio in the death group were lower than that in the survival group. The AUC values of age, white blood cell count, neutrophil count, creatinine, APTT, red blood cell count, hemoglobin, hematocrit and prothrombin ratio to distinguish between the survival and death groups range from 0.7 to 0.8 with p<0.05; Conclusion: The death group had a higher rate of underlying disease, shock, consciousness disorder than that in the survival group. Age, white blood cell count, neutrophil count, creatinine, APTT, red blood cell count, hemoglobin, hematocrit can be used to distinguish between survival and death groups in patients with severe dengue fever (p<0,05).