ISSN: 1859 - 2872
Assess the value of urinary L-FABP concentrations in response to rigorous-intensity exercise
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Abstract
Objective: To assess the value of urinary L-FABP concentrations in response to rigorous-intensity exercise and the potential correlation with varying exercise intensities. Subject and method: We conducted a cross-sectional, prospective descriptive study at unit X, laboratory was performed at 108 Military Central Hospital from January 2022 to December 2022, involving healthy soldiers ≥ 18 years old, excluding those with chronic kidney disease. The variables of interest included clinical measurements, serum urea and creatinine concentrations, and urinary L-FABP concentrations collected pre and post-exercise. Subsequently, we assessed variations in urinary L-FABP concentrations before and after exercise, in comparison to changes in serum urea and creatinine concentrations. This analysis aims to elucidate correlations of aforementioned variables between pre- and post-exercise states, and in response to varying intensities of physical training. Result: A total of 300 subjects were selected for the study. Urinary L-FABP concentration after exercise increased statistically significantly higher than before exercise (p<0.001). There was no correlation between post-exercise urinary L-FABP concentrations and post-exercise blood urea (p = 0.76) and blood creatinine (p = 0.163) concentrations. There was a positive correlation between urinary L-FABP concentration and exercise intensity (r = 0.421, p<0.001). Conclusion: An increase in urinary L-FABP concentrations in response to vigorous intensity exercise was shown in this study. There was also a positive correlation between the increase in post-exercise urine L-FABP concentration and exercise intensity.
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References
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