Mối liên quan giữa đặc điểm lâm sàng của nấm móng với các chủng nấm gây bệnh

Abstract

Objective: To investigate the association between clinical characteristics of fungal nail infection and causative fungal strains. Subject and method: A cross-sectional descriptive study was conducted on 110 patients diagnosed with fungal nail infection through fungal culture at the National Hospital of Dermatology and Venereology from August 2018 to July 2019. Result: Among 110 patients with onychomycosis, 22 patients (20%) had dermatophtye infections, 84 patients (76.4%) had yeast infections, and 4 patients (3.6%) had mold infections. Among the isolated fungal strains, C. krusei and C. albicans accounted for the highest proportion (40/110; 36.4%) and (27/110; 24.5%), respectively, followed by Trichopyton spp. (11/110; 10%). Perionychial inflammation was more common in patients infected with yeast than those infected with dermatophytes or and molds. The proportion of patients with proximal subungual onychomycosis infected with yeast was significantly higher than those infected with dermatophytes or molds (p=0.001). The proportion of superficial onychomycosis infected with dermatophytes was significantly higher than those infected with yeast or molds (p<0.0001). There was no difference in the subjective symptoms or location of nail infection (fingers or toes) among three causative fungal groups. Conclusion: The proportion of onychomycois patients infected with yeast (76.4%) was higher than those infected with dermatophytes and molds. Patients infected with yeast are more likely to have perionychial inflammation and proximal subungual onychomycosis than those infected with dermatophytes or molds. Superficial onychomycosis were more common in patients infected with dermatophytes than those infected with yeast or molds.