Impact of sarcopenia on the short-term outcome of elderly patients with chronic heart failure
Main Article Content
Keywords
Abstract
Objective: The study aimed to determine the prevalence of 3-month mortality and hospital readmission rates in older chronic heart failure patients with sarcopenia. Subject and method: A cross-sectional descriptive and longitudinal follow-up study was conducted among patients aged 60 or above with chronic heart failure discharged at the Cardiovascular Center, Thong Nhat Hospital, Ho Chi Minh City, and Vinh Long General Hospital from September 2021 to May 2022. Sarcopenia was defined according to the Asian Working Group for Sarcopenia 2019, and participants were followed for at least 3 months post-discharge. Result: The study enrolled 387 patients with chronic heart failure, with an average age of 74.6 years. Females represented 54.8% of the patients, while males accounted for 45.2%. The prevalence of sarcopenia was found to be 48.1%. During the 3-month follow-up, patients with sarcopenia had a significantly higher rate of readmission compared to non-sarcopenia patients (22% vs. 10.6%, RR 2.54, p<0.001). However, there was no significant difference in overall mortality between the two groups (3.4% vs. 2.8%, p=0.54). Conclusion: The prevalence of sarcopenia in older patients with chronic heart failure was relatively high. Sarcopenia was an independent risk factor for increased re-hospitalization 3 months after discharge.
Article Details
References
2. Van Ancum JM, Pijnappels M, Jonkman NH et al (2018) Muscle mass and muscle strength are associated with pre-and post-hospitalization falls in older male inpatients: A longitudinal cohort study. BMC Geriatr 8(1): 116.
3. Ponikowski P, Voors A, Anker S et al (2016) ESC Guidelines for the diagnosis and treatment of acute and chronic heart failure: The Task Force for the diagnosis and treatment of acute and chronic heart failure of the European Society of Cardiology (ESC). Developed with the special contribution of the Heart Failure Association (HFA) of the ESC. European Heart Journal 37: 2129-2200.
4. Huỳnh Trung Sơn (2017) Đánh giá nguy cơ suy dinh dưỡng trên bệnh nhân cao tuổi nhập viện bằng công cụ MNA-SF. Luận văn bác sĩ nội trú Đại học Y dược thành phố Hồ Chí Minh.
5. Chen LK, Woo J, Assantachai P et al (2020) Asian working group for sarcopenia: 2019 consensus update on sarcopenia diagnosis and treatment. J Am Med Dir Assoc Mar 21(3): 300-307.e2.
6. Zhao W, Lu M, Wang X, et al (2021) The role of sarcopenia questionnaires in hospitalized patients with chronic heart failure. Aging Clin Exp Res 33(2): 339-344.
7. Attaway A, Bellar A, Faty Dieye F, Wajda D, Dasarathy S (2021) Clinical impact of compound sarcopenia in hospitalized older adult patients with heart failure. J Am Geriatr Soc 69(7): 18151825.
8. Heidenreich PA, Bozkurt B, Aguilar D et al (2022) AHA/ACC/HFSA guideline for the management of heart failure: a report of the American College of Cardiology/American Heart Association Joint Committee on Clinical Practice Guidelines. Circulation 145: 895–1032.
9. Konishi M, Kagiyama N, Kamiya K, Saito H, Saito K et al (2020) Impact of sarcopenia on prognosis in patients with heart failure with reduced and preserved ejection fraction. Eur J Prev Cardiol 28(9): 1022-1029.
10. Lopez PD, Nepal P, Akinlonu A, Nekkalapudi D, Kim K, Cativo EH, Pekler G (2019) Low skeletal muscle mass independently predicts mortality in patients with chronic heart failure after an acute hospitalization. Cardiology 142(1): 28-36.