Cardio-ankle vascular index and associated factors in patients with chronic coronary artery disease
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Abstract
Objective: To investigate the characteristics of the cardio-ankle vascular index (CAVI) and its relationship with some clinical and paraclinical factors in patients with chronic coronary artery disease (CAD) or chronic coronary artery syndrome (according to ESC-2019). Subject and method: A cross-sectional study included 222 inpatients at Duc Giang General Hospital - Hanoi, divided into 2 groups with chronic CAD(+) and control group with CAD(-). Collected information includes: Age, gender, history of cardiovascular risk factors, clinical characteristics, hematological parameters, blood biochemistry, electrocardiography, echocardiography, CAVI results (right and left), and risk of cardiovascular disease according to the Framingham score. Pearson correlation coefficient (r) was used to evaluate the correlation between CAVI and quantitative variables. Result: The mean CAVI of the CAD(+) group was 9.20 ± 0.80, significantly higher than the CAD (-) group which was 8.48 ± 0.63 (p<0.001). CAVI had a weak positive correlation with systolic blood pressure (SBP) (r=0.263, p=0,001), Framingham score (r=0.355, p<0.001), PTP (r=0.214, p=0.007), number of combination of risk factors (r=0.188, p=0.017). CAVI increased significantly in patients with hypertension (9.25 ± 0.77 vs 8.87 ± 0.92, p=0.039). CAVI had weak negavetive correlations with eGFR in the CAD(-) group. Conclusion: The mean CAVI of the CAD(+) group increased higher than the control group. Related factors include SBP, hypertension, Framingham score and number of combination of risk factors.
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