ISSN: 1859 - 2872
Clinical, laboratory data, and treatment outcomes in patients with strongyloides stercoralis infection at University Medical Center Ho Chi Minh City
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Abstract
Objective: This retrospective study was carried out to describe the clinical, laboratory data, and treatment outcomes of strongyloidiasis cases at University Medical Center of Ho Chi Minh City to aid in early diagnosis. Subject and method: The data of patients who were admitted to the Gastroenterology Department of University Medical Center of Ho Chi Minh City from January 2018 to December 2022 were examined. The diagnosis of strongyloidiasis relies on identifying larvae in stool and/or the positive of the serologic test without prior treatment. The following information was collected: Clinical manifestation, laboratory test, abdominal imaging, treatment course, and follow-up. Result: A total of 163 patients who satisfied the inclusion criteria were retrospectively reviewed. Their median age was 68 (23-97) and male was predominant (73%). Abdominal pain (63.2%), nausea (50.3%), diarrhea (46%), and fatigue (76.7%) were the four most common symptoms. The immunocompromised state appears to be the risk factor for strongyloidiasis, with 64.4% of cases. Of which, long-term steroids use was the most prominent (23.3%). More than half of the cases (57.1% and 65%, respectively) had hypereosinophilia and hypoalbuminemia. Severe hyponatremia was also a notable feature, accounting for nearly one-fifth of all cases (17.3%). Except in 17 out of 163 cases (10.4%), the response to ivermectin was excellent. Conclusion: Strongyloidiasis should be suspected in patients who are immunocompromised, have multiple chronic diseases, have gastrointestinal symptoms, eosinophilia and/or hypoalbuminemia.
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References
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