Results of intravenous azithromycin in treating Mycoplasma pneumonia in children: A case series study

  • Nguyễn Thị Thanh Phúc Bệnh viện Nhi Trung ương
  • Trần Thanh Tú Bệnh viện Nhi Trung ương
  • Nguyễn Thị Hồng Hà Bệnh viện Nhi Trung ương
  • Phan Ngọc Bệnh viện Nhi Trung ương
  • Đinh Thị Hoa Bệnh viện Nhi Trung ương
  • Vũ Đức Anh Bệnh viện Nhi Trung ương
  • Nguyễn Ngọc Văn Bệnh viện Nhi Trung ương
  • Nguyễn Thị Thu Hằng Bệnh viện Nhi Trung ương
  • Đỗ Thị Hậu Bệnh viện Nhi Trung ương
  • Vũ Thị Hải Oanh Bệnh viện Nhi Trung ương

Main Article Content

Keywords

Mycoplasma pneumonia, azithromycin IV

Abstract

Objective: To evaluate the efficacy and safety of IV azithromycin to treat pneumonia cause by Mycoplasma pneumonia in children. Subject and method: A case series conducted at The International Department - National Children Hospital in Vietnam from March to July 2023 involving hospitalised chidren receiving IV azithromycin to treat Mycoplasma pneumonia. Result: There were 59 out of 61 children reported to achieve a full recovery with IV azithromycin. Two cases required a change of treatment due to either allergic reactions with the history of azithromycin allergy. No cases reported to develop kidney or liver function failure. Conclusion: IV azithromycin is effective and safe in treating young children suffered from pneumonia caused by Mycoplasma pneumonia.

Article Details

References

1. Jain S, Williams DJ, Arnold SR et al (2015) Community-acquired pneumonia requiring hospitalization among U.S. children. N Engl J Med 372(9): 835-845.
2. Kleigman R, Geme J, Blum N, Shah S, Wilson K, Tasker R (2019) Nelson Textbook of Pediatrics. 21st ed. Philadelphia PA: Elsevier: 1609.
3. Singlas E (1995) Clinical pharmacokinetics of azithromycin. Pathol Biol (Paris) 43(6): 505–511.
4. Kong W, Mao W, Zhang L et al (2023) Disproportionality analysis of quinolone safety in children using data from the FDA adverse event reporting system (FAERS). Front Pediatr 10.
5. Tetracycline (Antibiotics) Uses, Dosage, Side Effects. Drugs.com, , accessed: 27/09/2023.
6. Pereyre S, Goret J, Bébéar C (2016) Mycoplasma pneumoniae: Current knowledge on macrolide resistance and treatment. Front Microbiol 7: 974.
7. Matsuda K, Narita M, Sera N et al (2013) Gene and cytokine profile analysis of macrolide-resistant Mycoplasma pneumoniae infection in Fukuoka, Japan. BMC Infect Dis 13: 591.
8. Bộ Y tế (2014) Tài liệu hướng dẫn kỹ năng lồng ghép chăm sóc trẻ bệnh.
9. Jang MS, Kim BG, Kim J (2021) Prediction model for prolonged fever in patients with Mycoplasma pneumoniae pneumonia: A retropective study of 716 pediatric patient. BMC Pulm Med 21(1): 168. doi: 10.1186/s12890-021-01534-2.
10. Bệnh viện Nhi Trung ương (2016) Cẩm nang hướng dẫn sử dụng dịch vụ xét nghiệm sinh hóa.

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Published
Dec 29, 2023
DOI: https://doi.org/10.52389/ydls.v18i8.2079
Issue
Volume 18-No 8/2023
Section
Articles
How to Cite
PhúcN. T. T., TúT. T., HàN. T. H., NgọcP., Hoa Đinh T., AnhV. Đức, VănN. N., HằngN. T. T., Hậu Đỗ T., & OanhV. T. H. (2023). Results of intravenous azithromycin in treating Mycoplasma pneumonia in children: A case series study. Tạp Chí Y Dược lâm sàng 108, 18(8). https://doi.org/10.52389/ydls.v18i8.2079