ISSN: 1859 - 2872
Lymph nodes metastasis: Imaging characteristics and efficacy of detection with multi-slice computed tomography in patients with gastric cancer
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Abstract
Objective: To describe imaging characteristics and determine the efficacy of multi-slice computed tomography in the detection of lymphadenopathy in patients with gastric cancer. Subject and method: Multi-slice computed tomography was performed on 108 patients with gastric cancer. In our study, 1357 lymph nodes (408 positive, 949 negative for metastasis) were resected at surgery. Findings at CT and resection were cornpared. Sensitivity for detecting lymph nodes was evaluated according to nodal size and enhancement characteristics. Result: 528 of 1357 lymph nodes resected at surgery were detected on computed tomography, including 224 nodes 4-6mm (42.4%), 141 nodes 6-8mm (26.7%), 98 nodes 8-10mm (18.6%), 65 nodes > 10mm (12.3%). There was a statistically significant difference between metastasis-positive nodes and metastasis-negative nodes in the enhancement (68.4 ± 20.5HU vs 52.9 ± 15.5HU) and short axis diameter (9.66 ± 5.47mm vs 7.12 ± 2.50mm, p<0.05). The AUROC for lymph node size was 0.663 and the optimal cut-off point was 7.5mm, with a sensitivity of 60.4% and a specificity of 64.9%. Conclusion: Multi-slide computed tomography is effecfive for detection of metastatic lymphadenopathy from gastric cancer. CT attenuation and lymph node configuration aid in diagnosis of malignant adenopathy.
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References
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