ISSN: 1859 - 2872
Inflammatory bowel disease in autoimmune arthritis
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Abstract
Inflammatory bowel disease (IBD) includes two main diseases: Crohn's disease (CD) and ulcerative colitis (UC) that is characterized by chronic inflammatory of the gastrointestinal tract (GI) with remission and relapsing nature. Prolonged inflammation results in damage to the GI tract. The disease is common in all regions of the world, more common in western countries and has an increasing trend. In addition to damage in GI, the disease also manifests in many other organs, in which arthritis is one of the common extra-intestinal manifestations of IBD, accounting for 10-20%. Arthritis in IBD is mainly peripheral large joints, a few are symmetrical small joints and axial spondyloarthropathies (axial SpA), most do not cause joint deformity. Genetic and autoimmune factors implicated in the pathogenesis of both inflammatory bowel disease and arthritis. Diagnosis of IBD is still difficult, there is no single criterion that must combine multimodality to confirm the diagnosis. There have been many advances in the treatment of IBD, where individualization of treatment and the introduction of biologic drugs hold great promise.
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References
2. Fragoulis GE, Liava C, Daoussis D et al (2019) Inflammatory bowel diseases and spondyloarthropathies: From pathogenesis to treatment. World J Gastroenterol 25(18): 2162-2176.
3. GBD 2017 Inflammatory Bowel Disease Collaborators (2020) The global, regional, and national burden of inflammatory bowel disease in 195 countries and territories, 1990-2017: A systematic analysis for the Global Burden of Disease Study 5(1): 17-30
4. Nakase H, Uchino M, Shinzaki S, Matsuura M, Matsuoka K, Kobayashi T, Saruta M, Hirai F, Hata K, Hiraoka S, Esaki M, Sugimoto K, Fuji T, Watanabe K, Nakamura S, Inoue N, Itoh T, Naganuma M, Hisamatsu T, Watanabe M, Miwa H, Enomoto N, Shimosegawa T, Koike K (2021) Evidence-based clinical practice guidelines for inflammatory bowel disease 2020. J Gastroenterol 56(6): 489-526.
5. Levine JS, Burakoff R (2011) Extraintestinal manifestations of inflammatory bowel disease. Gastroenterol Hepatol (N Y) 7(4): 235-241.
6. Agrawal M, Spencer EA, Colombel JF, Ungaro RC (2021) Approach to the management of recently diagnosed inflammatory bowel disease patients: A user’s guide for adult and pediatric gastroenterologists. Gastroenterology 161(1): 47-65.
7. Orchard TR, Wordsworth BP, Jewell DP (1998) Peripheral arthropathies in inflammatory bowel disease: Their articular distribution and natural history. Gut 42: 387-91.
8. Stolwijk C, Essers I, Van Tubergen A (2015), Epidemiology of extra-articular manifestations in ankylosing spondylitis: A population-based cohort study. Ann Rheum Dis 74: 1373-1378.
9. Peluso R, Manguso F, Vitiello M, Iervolino S, Di Minno MN (2015) Management of arthropathy in inflammatory bowel diseases. Ther Adv Chronic Dis 6(2): 65-77.
10. Orchard TR (2012) Management of arthritis in patients with inflammatory bowel disease. Gastroenterol Hepatol 8(5): 327-329.
11. Fragoulis GE, Liava C, Daoussis D, Akriviadis E, Garyfallos A, Dimitroulas T (2019) Inflammatory bowel diseases and spondyloarthropathies: From pathogenesis to treatment. World J Gastroenterol 25(18): 2162-2176.
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