ISSN: 1859 - 2872
Clinical, subclinical characteristics and factors related to early seizure supratentorial post-stroke
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Abstract
Objective: To determine the clinical, subclinical characteristics and factors related to early supratentorial post-stroke epilepsy patients. Subject and method: A prospective descriptive study on 1061 supratentorial post-stroke hospitalized at 108 Military Central Hospital and Phu Tho Provincial General Hospital from 2018 to 2022. All patients was clinical and subclinical examination, and follow-up until the patient is discharged. Result: There were 61/1061 stroke patients developing early onset seizures with motor-type and 68.9% had a generalized. There were 73.7% local seizure without loss of consciousness. The mean age was 61.5 ± 12.3 years old and male accounted for 77.0%. The mean Glasgow score was 14.2 ± 1.6 and the NIHSS score was 8.2 ± 1.6. CT-MRI recorded 57.1% left side, both cortical and subcortical areas were 32.1%, most were parietal and frontal lobes. 81.7% was infarct and one area of cerebral artery accounted for 75%. Factors related to early onset epilepsy were older age, male, previous cerebral stroke, lower Glasgow score, higher NIHSS score, mixed lesion area, frontal lobe lesion. Conclusion: Early seizures after stroke have motor and generalized pattern. Related factors were: Higher age, male, lower Glasgow score, higher NIHSS score, bilateral lesions, mixed lesion area, frontal lobe lesion.
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References
2. Waafi AK, Husna M, Damayanti R, Setijowati N (2023) Clinical risk factors related to post-stroke epilepsy patients in Indonesia: a hospital-based study. The Egyptian Journal of Neurology, Psychiatry and Neurosurgery 59(39).
3. Ma S, Fan X, Zhao X, Wang K, Wang H, Yang Y (2021) Risk factors for early–onset seizures after stroke: A systematic review and meta‐analysis of 18 observational studies. J Brain Behavior 11(6): 02142.
4. Zhang C, Wang X, Wang Y, Zhang JG, Hu W, Ge M, Zhang K, Shao X (2014) Risk factors for post-stroke seizures: A systematic review and meta-analysis. J Epilepsy research 108(10): 1806-1816.
5. Agarwal A, Sharma J, Padma Srivastava MV, Bhatia R, Singh MB, Gupta A, Pandit AK, Singh R, Rajan R, Dwivedi S, Upadhyay A, Garg A, Vishnu VY (2021) Early post stroke seizures in acute ischemic stroke: A prospective cohort study (1752). AAN Enterprises.
6. Aiwansoba IF, Chukwuyem OW (2014) Early post-acute stroke seizures: Clinical profile and outcome in a Nigerian stroke unit. Annals of African Medicine 13(1): 11-15.
7. Chen J, Ye H, Zhang J, Li A & Ni Y (2022) Pathogenesis of seizures and epilepsy after stroke. Acta Epileptologica 4: 1-6.
8. Goswami RP, Karmakar PS, Ghosh A (2012) Early seizures in first‐ever acute stroke patients in I ndia: Incidence, predictive factors and impact on early outcome. European Journal of Neurology 19(10): 1361-1366.
9. Guo X, Zhong R, Han Y, Zhang H, Zhang X, Lin W (2022) Incidence and relevant factors for seizures after spontaneous intracerebral hemorrhage: A systematic review and meta-analysis. Seizure 101: 30-38.
10. Hundozi Z, Shala A, Boshnjaku D, Bytyqi S, Rrustemi J, Rama M, Jashari F (2016) Hypertension on admission is associated with a lower risk of early seizures after stroke. Seizure 36: 40-43.
11. Mohamed C, Kissani N (2015) Early seizures in acute stroke. Pan African Medical Journal 20(1).
12. Phan J, Ramos M, Soares T, Parmar MS (2022) Poststroke Seizure and Epilepsy: A Review of Incidence, Risk Factors, Diagnosis, Pathophysiology, and Pharmacological Therapies. Oxidative Medicine and Cellular Longevity.
13. Waafi AK, Husna M, Damayanti R & Setijowati N (2023) Clinical risk factors related to post-stroke epilepsy patients in Indonesia: A hospital-based study. The Egyptian Journal of Neurology, Psychiatry and Neurosurgery 59(1): 1-9.
14. Wang JZ, Vyas MV, Saposnik G, Burneo JG (2017) Incidence and management of seizures after ischemic stroke: systematic review and meta-analysis. Neurology 89(12): 1220-1228.
15. Zhang C, Wang X, Wang Y, Zhang JG, Hu W, Ge M, Zhang K, Shao X (2014) Risk factors for post-stroke seizures: A systematic review and meta-analysis. Epilepsy research 108(10): 1806-1816.
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