ISSN: 1859 - 2872
A systematic review of telepharmacy for outpatients with chronic diseases
Main Article Content
Keywords
Telepharmacy, pharmacist, intervention, chronic disease
Abstract
Objective: The study aims to provide comprehensive knowledge about telepharmacy for outpatients with chronic diseases and its effectiveness. Subject and method: We searched the PubMed database from January 2001 to March 2021 for original studies of telepharmacy for outpatients with chronic diseases that reported clinical outcomes, medication adherence, or quality of life. Result: Total 42 studies were included and of those, 31 (73.8%) were clinical trials. Most studies used phone calls (69.0%) or video calls (21.4%). The telepharmacy services consisted of medication review (83.3%), patient education (76.2%), and patient counselling (76.2%). Most studies combined these 2 or 3 services (85.7%). Telepharmacy was almost carried out by pharmacists (76.2%) during the common intervention period of 6 or 12 months (23.8% và 30.9%). 21/32 studies that reported clinical outcomes and 9/19 studies that evaluated medication adherence demonstrated the effectiveness of telepharmacy. Conclusion: Telepharmacy could increase the effectiveness of clinical outcomes, medication adherence, and quality of life of outpatients with chronic diseases.
Article Details
References
1. Bộ Y tế (2020) Quyết định số 5316/QĐ-BYT “Phê duyệt chương trình chuyển đổi số y tế đến năm 2025, định hướng đến năm 2030.
2. Bộ Y tế (2020) Quyết định số 1588/QĐ-BYT về việc ban hành tài liệu chuyên môn "Hướng dẫn tạm thời quản lý sức khỏe người cao tuổi, người mắc bệnh mạn tính tại tuyến y tế cơ sở trong bối cảnh dịch COVID-19.
3. Bộ Y tế (2020) Quyết định số 2628/QĐ - BYT phê duyệt Đề án "Khám, chữa bệnh từ xa" giai đoạn 2020 - 2025 .
4. Bộ Y tế (2016) Thông tư 46/2016/TT-BYT ban hành danh mục bệnh chữa trị dài ngày.
5. Bộ Y tế (2019) Hướng dẫn thực hành dược lam sàng cho Dược sỹ trong một số bệnh không lây nhiễm, Hà Nội.
6. Bộ Y tế (2020), Quy định về tổ chức, hoạt động dược lâm sàng của cơ sở khám bệnh, chữa bệnh, Hà Nội.
7. Aberger EW, Migliozzi D et al (2014) Enhancing patient engagement and blood pressure management for renal transplant recipients via home electronic monitoring and web-enabled collaborative care. Telemed J E Health 20(9): 850-854.
8. Alexander Emily, Butler C David et al (2017) ASHP statement on telepharmacy. American Journal of Health-System Pharmacy 74(9): 236-241.
9. Alves da Costa Filipa, van Mil JW Foppe et al (2019) Correction to: The Pharmacist Guide to Implementing Pharmaceutical Care. The Pharmacist Guide to Implementing Pharmaceutical Care, Alves da Costa Filipa, van Mil J. W. Foppe,Alvarez-Risco Aldo, Springer International Publishing, Cham: 1.
10. Asche SE, O'Connor PJ et al (2016) Patient characteristics associated with greater blood pressure control in a randomized trial of home blood pressure telemonitoring and pharmacist management. J Am Soc Hypertens 10(11): 873-880.
11. Baker JW, Forkum W et al (2019) Utilizing clinical video telehealth to improve access and optimize pharmacists' role in diabetes management. J Am Pharm Assoc 59(2): 63-66.
12. Bosworth HB, Olsen MK et al (2018) Telemedicine cardiovascular risk reduction in veterans: The CITIES trial. Am Heart J 199: 122-129.
13. Brown W, Scott D et al (2017) Impact of telepharmacy services as a way to increase access to asthma care. J Asthma 54(9): 961-967.
14. Buis LR, Roberson DN et al (2020) Understanding the Feasibility, Acceptability, and Efficacy of a Clinical Pharmacist-led Mobile Approach (BPTrack) to Hypertension Management: Mixed Methods Pilot Study. J Med Internet Res 22(8): 19882.
15. Bynum A, Hopkins D et al (2001) The effect of telepharmacy counseling on metered-dose inhaler technique among adolescents with asthma in rural Arkansas. Telemed J E Health 7(3): 207-17.
16. Cao H, Jiang S et al (2021) Effectiveness of the Alfalfa App in Warfarin Therapy Management for Patients Undergoing Venous Thrombosis Prevention and Treatment: Cohort Study. JMIR Mhealth Uhealth 9(3): 23332.
17. Cao H, Wu J et al (2018) Outcomes of warfarin therapy managed by pharmacists via hospital anticoagulation clinic versus online anticoagulation clinic. Int J Clin Pharm 40(5): 1072-1077.
18. Carter BL, Levy B et al (2018) Cluster-randomized trial to evaluate a centralized clinical pharmacy service in private family medicine offices. Circ Cardiovasc Qual Outcomes 11(6): e004188.
19. Case L, Wright J et al (2019) Comparison of hepatitis C treatment outcomes between telehepatology and specialty care clinics in the era of direct-acting antivirals. J Telemed Telecare 1357633x19885750.
20. Cohen LB, Taveira TH et al (2020) Pharmacist-led telehealth disease management program for patients with diabetes and depression. J Telemed Telecare 26(5): 294-302.
21. Cole J, Wilkins N et al (2019) Impact of Pharmacist Involvement on Telehealth Transitional Care Management (TCM) for High Medication Risk Patients. Pharmacy (Basel) 7(4).
22. Elbeddini A Prabaharan T et al (2020) Pharmacists and COVID-19. J Pharm Policy Pract 13: 36.
23. eReynolds R, Dennis S et al (2018) A systematic review of chronic disease management interventions in primary care. BMC Family Practice 19(1): 11.
24. Fortney JC, Pyne JM et al (2015) Telemedicine-based collaborative care for posttraumatic stress disorder: A randomized clinical trial. JAMA Psychiatry 72(1): 58-67.
25. Fortney JC, Pyne JM et al (2013) Practice-based versus telemedicine-based collaborative care for depression in rural federally qualified health centers: a pragmatic randomized comparative effectiveness trial. Am J Psychiatry 170(4): 414-425.
26. Greer N, Bolduc J et al (2015) VA Evidence-based Synthesis Program Reports. Pharmacist-Led Chronic Disease Management: A Systematic Review of Effectiveness and Harms Compared to Usual Care. Department of Veterans Affairs (US), Washington (DC).
27. Hawes EM, Lambert E et al (2018) Implementation and evaluation of a pharmacist-led electronic visit program for diabetes and anticoagulation care in a patient-centered medical home. Am J Health Syst Pharm 75(12): 901-910.
28. Hough S, McDevitt R et al (2021) Chemotherapy remote care monitoring program: Integration of SMS text patient-reported outcomes in the electronic health record and pharmacist intervention for chemotherapy-induced nausea and vomiting. JCO Oncol Pract Op2000639.
29. Ishani A, Christopher J et al (2016) Telehealth by an interprofessional team in patients with ckd: a randomized controlled trial. Am J Kidney Dis, 68(1): 41-49.
30. Klug C, Bonin K et al (2011) Integrating telehealth technology into a clinical pharmacy telephonic diabetes management program. J Diabetes Sci Technol 5(5): 1238-1245.
31. Kobe EA, Diamantidis CJ et al (2020) Racial differences in the effectiveness of a multifactorial telehealth intervention to slow diabetic kidney disease. Med Care 58(11): 968-973.
32. Kosse RC, Bouvy ML et al (2019) Effective engagement of adolescent asthma patients with mobile health-supporting medication adherence. JMIR Mhealth Uhealth 7(3): 12411.
33. Kosse RC, Bouvy ML et al (2019) Effect of a mHealth intervention on adherence in adolescents with asthma: A randomized controlled trial. Respir Med 149: 45-51.
34. La Regina R, Pandolfi D et al (2020) A new case manager for diabetic patients: A pilot observational study of the role of community pharmacists and pharmacy services in the case management of diabetic patients. Pharmacy (Basel) 8(4).
35. Li X, Zuo C et al (2020) Evaluation of Remote Pharmacist-Led Outpatient Service for Geriatric Patients on Rivaroxaban for Nonvalvular Atrial Fibrillation During the COVID-19 Pandemic. Front Pharmacol 11: 1275.
36. Littauer SL, Dixon DL et al (2017) Pharmacists providing care in the outpatient setting through telemedicine models: A narrative review. Pharm Pract (Granada) 15(4): 1134.
37. Locke ER, Thomas RM, et al (2019) Using video telehealth to facilitate inhaler training in rural patients with obstructive lung disease. Telemed J E Health 25(3): 230-236.
38. Margolis KL, Asche SE et al (2013) Effect of home blood pressure telemonitoring and pharmacist management on blood pressure control: A cluster randomized clinical trial. Jama, 310(1): 46-56.
39. Margolis KL, Asche SE et al (2015) A successful multifaceted trial to improve hypertension control in primary care: Why did it work?. J Gen Intern Med 30(11): 1665-1672.
40. Margolis KL, Asche SE et al (2018) Long-term outcomes of the effects of home blood pressure telemonitoring and pharmacist management on blood pressure among adults with uncontrolled hypertension: follow-up of a cluster randomized clinical trial. JAMA Netw Open 1(5):181617.
41. Margolis KL, Dehmer SP et al (2020) Cardiovascular Events and Costs With Home Blood Pressure Telemonitoring and Pharmacist Management for Uncontrolled Hypertension. Hypertension 76(4): 1097-1103.
42. Margusino-Framiñán L, Illarro-Uranga et al (2020) Pharmaceutical care to hospital outpatients during the COVID-19 pandemic. Telepharmacy. Farm Hosp 44(7): 61-65.
43. Martínez-Santana V, Boix-Montañés A et al (2020) Remote pharmaceutical care for patients with rheumatoid arthritis and psoriasis. Int J Clin Pharm.
44. Maxwell LG, McFarland MS et al (2016) Evaluation of the impact of a pharmacist-led telehealth clinic on diabetes-related goals of therapy in a veteran population. Pharmacotherapy 36(3): 348-356.
45. McFarland M, Davis K et al (2012) Use of home telehealth monitoring with active medication therapy management by clinical pharmacists in veterans with poorly controlled type 2 diabetes mellitus. Pharmacotherapy 32(5): 420-426.
46. Niznik JD, He H et al (2018) Impact of clinical pharmacist services delivered via telemedicine in the outpatient or ambulatory care setting: A systematic review. Res Social Adm Pharm 14(8): 707-717.
47. Pathak S, Haynes M et al (2020) Telepharmacy and quality of medication use in rural areas, 2013-2019. Prev Chronic Dis 17: E101.
48. Pawloski PA, Asche SE, et al (2016) A substudy evaluating treatment intensification on medication adherence among hypertensive patients receiving home blood pressure telemonitoring and pharmacist management. J Clin Pharm Ther 41(5): 493-498.
49. Ralston JD, Cook AJ, et al (2014) Home blood pressure monitoring, secure electronic messaging and medication intensification for improving hypertension control: A mediation analysis. Appl Clin Inform 5(1): 232-248.
50. Rickles NM, Svarstad BL, et al (2005) Pharmacist telemonitoring of antidepressant use: Effects on pharmacist-patient collaboration. J Am Pharm Assoc 45(3): 344-353.
51. Schmidt S, Sheikzadeh S, et al (2008) Acceptance of telemonitoring to enhance medication compliance in patients with chronic heart failure. Telemed J E Health 14(5): 426-433.
52. Shane-McWhorter L, McAdam-Marx C et al (2015) Pharmacist-provided diabetes management and education via a telemonitoring program. J Am Pharm Assoc 5(5): 516-526.
53. Sudas Na, Ayutthaya N, Sakunrak I et al (2018) Clinical Outcomes of Telemonitoring for Patients on Warfarin after Discharge from Hospital. Int J Telemed Appl: 7503421.
54. Taylor AM, Bingham J et al (2018) Integrating innovative telehealth solutions into an interprofessional team-delivered chronic care management pilot program. J Manag Care Spec Pharm 24(8): 813-818.
55. Thomas RM, Locke ER et al (2017) Inhaler training delivered by internet-based home videoconferencing improves technique and quality of life. Respir Care 62(11): 1412-1422.
56. Updike WH, Pane O et al (2020) Pharmacists interventions using Bluetooth technology and telehealth to improve blood pressure-A pilot study. J Am Pharm Assoc 60(4): 100-108.
57. Young HN, Havican SN et al (2012) Patient and phaRmacist telephonic encounters (PARTE) in an underserved rural patient population with asthma: Results of a pilot study. Telemed J E Health 18(6): 427-433.
2. Bộ Y tế (2020) Quyết định số 1588/QĐ-BYT về việc ban hành tài liệu chuyên môn "Hướng dẫn tạm thời quản lý sức khỏe người cao tuổi, người mắc bệnh mạn tính tại tuyến y tế cơ sở trong bối cảnh dịch COVID-19.
3. Bộ Y tế (2020) Quyết định số 2628/QĐ - BYT phê duyệt Đề án "Khám, chữa bệnh từ xa" giai đoạn 2020 - 2025 .
4. Bộ Y tế (2016) Thông tư 46/2016/TT-BYT ban hành danh mục bệnh chữa trị dài ngày.
5. Bộ Y tế (2019) Hướng dẫn thực hành dược lam sàng cho Dược sỹ trong một số bệnh không lây nhiễm, Hà Nội.
6. Bộ Y tế (2020), Quy định về tổ chức, hoạt động dược lâm sàng của cơ sở khám bệnh, chữa bệnh, Hà Nội.
7. Aberger EW, Migliozzi D et al (2014) Enhancing patient engagement and blood pressure management for renal transplant recipients via home electronic monitoring and web-enabled collaborative care. Telemed J E Health 20(9): 850-854.
8. Alexander Emily, Butler C David et al (2017) ASHP statement on telepharmacy. American Journal of Health-System Pharmacy 74(9): 236-241.
9. Alves da Costa Filipa, van Mil JW Foppe et al (2019) Correction to: The Pharmacist Guide to Implementing Pharmaceutical Care. The Pharmacist Guide to Implementing Pharmaceutical Care, Alves da Costa Filipa, van Mil J. W. Foppe,Alvarez-Risco Aldo, Springer International Publishing, Cham: 1.
10. Asche SE, O'Connor PJ et al (2016) Patient characteristics associated with greater blood pressure control in a randomized trial of home blood pressure telemonitoring and pharmacist management. J Am Soc Hypertens 10(11): 873-880.
11. Baker JW, Forkum W et al (2019) Utilizing clinical video telehealth to improve access and optimize pharmacists' role in diabetes management. J Am Pharm Assoc 59(2): 63-66.
12. Bosworth HB, Olsen MK et al (2018) Telemedicine cardiovascular risk reduction in veterans: The CITIES trial. Am Heart J 199: 122-129.
13. Brown W, Scott D et al (2017) Impact of telepharmacy services as a way to increase access to asthma care. J Asthma 54(9): 961-967.
14. Buis LR, Roberson DN et al (2020) Understanding the Feasibility, Acceptability, and Efficacy of a Clinical Pharmacist-led Mobile Approach (BPTrack) to Hypertension Management: Mixed Methods Pilot Study. J Med Internet Res 22(8): 19882.
15. Bynum A, Hopkins D et al (2001) The effect of telepharmacy counseling on metered-dose inhaler technique among adolescents with asthma in rural Arkansas. Telemed J E Health 7(3): 207-17.
16. Cao H, Jiang S et al (2021) Effectiveness of the Alfalfa App in Warfarin Therapy Management for Patients Undergoing Venous Thrombosis Prevention and Treatment: Cohort Study. JMIR Mhealth Uhealth 9(3): 23332.
17. Cao H, Wu J et al (2018) Outcomes of warfarin therapy managed by pharmacists via hospital anticoagulation clinic versus online anticoagulation clinic. Int J Clin Pharm 40(5): 1072-1077.
18. Carter BL, Levy B et al (2018) Cluster-randomized trial to evaluate a centralized clinical pharmacy service in private family medicine offices. Circ Cardiovasc Qual Outcomes 11(6): e004188.
19. Case L, Wright J et al (2019) Comparison of hepatitis C treatment outcomes between telehepatology and specialty care clinics in the era of direct-acting antivirals. J Telemed Telecare 1357633x19885750.
20. Cohen LB, Taveira TH et al (2020) Pharmacist-led telehealth disease management program for patients with diabetes and depression. J Telemed Telecare 26(5): 294-302.
21. Cole J, Wilkins N et al (2019) Impact of Pharmacist Involvement on Telehealth Transitional Care Management (TCM) for High Medication Risk Patients. Pharmacy (Basel) 7(4).
22. Elbeddini A Prabaharan T et al (2020) Pharmacists and COVID-19. J Pharm Policy Pract 13: 36.
23. eReynolds R, Dennis S et al (2018) A systematic review of chronic disease management interventions in primary care. BMC Family Practice 19(1): 11.
24. Fortney JC, Pyne JM et al (2015) Telemedicine-based collaborative care for posttraumatic stress disorder: A randomized clinical trial. JAMA Psychiatry 72(1): 58-67.
25. Fortney JC, Pyne JM et al (2013) Practice-based versus telemedicine-based collaborative care for depression in rural federally qualified health centers: a pragmatic randomized comparative effectiveness trial. Am J Psychiatry 170(4): 414-425.
26. Greer N, Bolduc J et al (2015) VA Evidence-based Synthesis Program Reports. Pharmacist-Led Chronic Disease Management: A Systematic Review of Effectiveness and Harms Compared to Usual Care. Department of Veterans Affairs (US), Washington (DC).
27. Hawes EM, Lambert E et al (2018) Implementation and evaluation of a pharmacist-led electronic visit program for diabetes and anticoagulation care in a patient-centered medical home. Am J Health Syst Pharm 75(12): 901-910.
28. Hough S, McDevitt R et al (2021) Chemotherapy remote care monitoring program: Integration of SMS text patient-reported outcomes in the electronic health record and pharmacist intervention for chemotherapy-induced nausea and vomiting. JCO Oncol Pract Op2000639.
29. Ishani A, Christopher J et al (2016) Telehealth by an interprofessional team in patients with ckd: a randomized controlled trial. Am J Kidney Dis, 68(1): 41-49.
30. Klug C, Bonin K et al (2011) Integrating telehealth technology into a clinical pharmacy telephonic diabetes management program. J Diabetes Sci Technol 5(5): 1238-1245.
31. Kobe EA, Diamantidis CJ et al (2020) Racial differences in the effectiveness of a multifactorial telehealth intervention to slow diabetic kidney disease. Med Care 58(11): 968-973.
32. Kosse RC, Bouvy ML et al (2019) Effective engagement of adolescent asthma patients with mobile health-supporting medication adherence. JMIR Mhealth Uhealth 7(3): 12411.
33. Kosse RC, Bouvy ML et al (2019) Effect of a mHealth intervention on adherence in adolescents with asthma: A randomized controlled trial. Respir Med 149: 45-51.
34. La Regina R, Pandolfi D et al (2020) A new case manager for diabetic patients: A pilot observational study of the role of community pharmacists and pharmacy services in the case management of diabetic patients. Pharmacy (Basel) 8(4).
35. Li X, Zuo C et al (2020) Evaluation of Remote Pharmacist-Led Outpatient Service for Geriatric Patients on Rivaroxaban for Nonvalvular Atrial Fibrillation During the COVID-19 Pandemic. Front Pharmacol 11: 1275.
36. Littauer SL, Dixon DL et al (2017) Pharmacists providing care in the outpatient setting through telemedicine models: A narrative review. Pharm Pract (Granada) 15(4): 1134.
37. Locke ER, Thomas RM, et al (2019) Using video telehealth to facilitate inhaler training in rural patients with obstructive lung disease. Telemed J E Health 25(3): 230-236.
38. Margolis KL, Asche SE et al (2013) Effect of home blood pressure telemonitoring and pharmacist management on blood pressure control: A cluster randomized clinical trial. Jama, 310(1): 46-56.
39. Margolis KL, Asche SE et al (2015) A successful multifaceted trial to improve hypertension control in primary care: Why did it work?. J Gen Intern Med 30(11): 1665-1672.
40. Margolis KL, Asche SE et al (2018) Long-term outcomes of the effects of home blood pressure telemonitoring and pharmacist management on blood pressure among adults with uncontrolled hypertension: follow-up of a cluster randomized clinical trial. JAMA Netw Open 1(5):181617.
41. Margolis KL, Dehmer SP et al (2020) Cardiovascular Events and Costs With Home Blood Pressure Telemonitoring and Pharmacist Management for Uncontrolled Hypertension. Hypertension 76(4): 1097-1103.
42. Margusino-Framiñán L, Illarro-Uranga et al (2020) Pharmaceutical care to hospital outpatients during the COVID-19 pandemic. Telepharmacy. Farm Hosp 44(7): 61-65.
43. Martínez-Santana V, Boix-Montañés A et al (2020) Remote pharmaceutical care for patients with rheumatoid arthritis and psoriasis. Int J Clin Pharm.
44. Maxwell LG, McFarland MS et al (2016) Evaluation of the impact of a pharmacist-led telehealth clinic on diabetes-related goals of therapy in a veteran population. Pharmacotherapy 36(3): 348-356.
45. McFarland M, Davis K et al (2012) Use of home telehealth monitoring with active medication therapy management by clinical pharmacists in veterans with poorly controlled type 2 diabetes mellitus. Pharmacotherapy 32(5): 420-426.
46. Niznik JD, He H et al (2018) Impact of clinical pharmacist services delivered via telemedicine in the outpatient or ambulatory care setting: A systematic review. Res Social Adm Pharm 14(8): 707-717.
47. Pathak S, Haynes M et al (2020) Telepharmacy and quality of medication use in rural areas, 2013-2019. Prev Chronic Dis 17: E101.
48. Pawloski PA, Asche SE, et al (2016) A substudy evaluating treatment intensification on medication adherence among hypertensive patients receiving home blood pressure telemonitoring and pharmacist management. J Clin Pharm Ther 41(5): 493-498.
49. Ralston JD, Cook AJ, et al (2014) Home blood pressure monitoring, secure electronic messaging and medication intensification for improving hypertension control: A mediation analysis. Appl Clin Inform 5(1): 232-248.
50. Rickles NM, Svarstad BL, et al (2005) Pharmacist telemonitoring of antidepressant use: Effects on pharmacist-patient collaboration. J Am Pharm Assoc 45(3): 344-353.
51. Schmidt S, Sheikzadeh S, et al (2008) Acceptance of telemonitoring to enhance medication compliance in patients with chronic heart failure. Telemed J E Health 14(5): 426-433.
52. Shane-McWhorter L, McAdam-Marx C et al (2015) Pharmacist-provided diabetes management and education via a telemonitoring program. J Am Pharm Assoc 5(5): 516-526.
53. Sudas Na, Ayutthaya N, Sakunrak I et al (2018) Clinical Outcomes of Telemonitoring for Patients on Warfarin after Discharge from Hospital. Int J Telemed Appl: 7503421.
54. Taylor AM, Bingham J et al (2018) Integrating innovative telehealth solutions into an interprofessional team-delivered chronic care management pilot program. J Manag Care Spec Pharm 24(8): 813-818.
55. Thomas RM, Locke ER et al (2017) Inhaler training delivered by internet-based home videoconferencing improves technique and quality of life. Respir Care 62(11): 1412-1422.
56. Updike WH, Pane O et al (2020) Pharmacists interventions using Bluetooth technology and telehealth to improve blood pressure-A pilot study. J Am Pharm Assoc 60(4): 100-108.
57. Young HN, Havican SN et al (2012) Patient and phaRmacist telephonic encounters (PARTE) in an underserved rural patient population with asthma: Results of a pilot study. Telemed J E Health 18(6): 427-433.
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Published
Oct 16, 2023
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Articles
How to Cite
ThảoN. T., Lan AnhP. T., & ThaoC. T. B. (2023). A systematic review of telepharmacy for outpatients with chronic diseases. Tạp Chí Y Dược lâm sàng 108, 18(dbv). https://doi.org/10.52389/ydls.v18idbv.2000