Các vấn đề liên quan đến thuốc trên bệnh nhân cao tuổi mắc đái tháo đường típ 2 điều trị ngoại trú tại Bệnh viện Hữu Nghị

Abstract

Objective: To identify drug-related problems (DRP) on prescriptions and behaviors with associated factors in elderly outpatients with type 2 diabetes mellitus (DM). Subject and method: Outpatients aged 60 years or older were diagnosed with type 2 diabetes and treated at the Diabetes - Endocrinology Division of Huu Nghi Hospital between December 2019 and January 2020. A cross-sectional using a whole-sample was conducted. Information on diseases and medications was collected from medical records, and drug using behaviors of patients were assessed through interviews. Pharmacists detected DRPs first and then discussed them with physician to get agreement. Result: A total of 447 patients participated. Total of 1125 DRPs were detected, or 2.5 DRPs on average per patient. DRPs were presented in 91.7% of prescriptions, the most typical DRP was a lack of clear instructions regarding how and when to take medications. Nearly 50% of patients had behavioral DRPs, the most common DRPs were non-adherence to medication use and incorrect insulin injection technique. Multivariate regression analysis revealed that the more drugs in the prescription, the higher the risk of DRPs on prescription (OR = 1.66; p=0.0002). Patients prescribed insulin more likely to experience behavioral DRP than those who were not (OR = 17.95, p<0.001). Conclusion: DRPs frequently affects elderly patients with diabetes. Standardizing prescribing software and providing patients with counseling and education may help prevent DRPs.