Prescription pattern of oral glucocorticoids at the Outpatient Department of 7A Military Hospital, 2022: A cross-sectional study

  • Cao Kim Xoa Trường Đại học Nguyễn Tất Thành

Main Article Content

Keywords

Oral corticoid, outpatient, prescription patterns, drug-drug interactions

Abstract

Objective: To investigate patterns of corticosteroids used for the treatment of outpatients in the 7A Military Hospital, thus helping to improve the effectiveness and safety of treatment. Subject and method: A descriptive cross-sectional study was conducted on 400 outpatients from August 1, 2022 to December 31, 2022 at outpatient department of the hospital to statistical analysis. Result: It was found that patients had an average age of 46.88 ± 15.88 (years), of which female patients accounted for 53.8%. The majority of systemic corticosteroids were prescribed for acute upper respiratory tract infections (58.5%), the main prescribed drug was prednisolone (82.3%). The proportion of prescriptions containing more than 5 drugs accounted for 54%, and treatment duration from 5 to 7 days accounted for the highest proportion (74.3%). Most oral GCs were prescribed once a day in the morning with 208 prescriptions (70%). There were 120 (30%) prescriptions with drug interactions searched by Lexicomp, besides Medscape and Drugs.com had 135 (33.7%) and 159 (39.7%) prescriptions respectively, the rate of serious interactions was relatively low. Conclusion: The study has provided an overview of the situation of prescribing oral GC drugs in outpatient treatment at 7A Military Hospital, providing more references for medical staffs.

Article Details

References

1. Williams DM (2018) Clinical pharmacology of corticosteroids. Respiratory care 63(6): 655-670.
2. Đào TDN, & Huỳnh TS (2022) Khảo sát tình hình sử dụng glucocorticoid trên bệnh nhân điều trị ngoại trú tại bệnh viện Nhân Dân Gia Định. Tạp chí Y học Việt Nam, 516(2).
3. Wondmkun YT & Ayele AG (2021) Assessment of prescription pattern of systemic steroidal drugs in the outpatient department of Menelik II Referral Hospital, Addis Ababa, Ethiopia, 2019. Patient preference and adherence: 9-14.
4. Dvorin EL & Ebell MH (2020) Short-term systemic corticosteroids: appropriate use in primary care. American Family Physician 101(2): 89-94.
5. CDC (2017) [cited 2019 Jan 4.Adult Treatment Recommendations.]. Truy cập tại: https://www.cdc.gov/antibiotic-use/community/for-hcp/outpatient-hcp/adult-treatment-rec.html.
6. Bộ Y tế (2018) Dược thư Quốc gia. Nhà xuất bản Y học Hà Nội, tr. 53, tr. 969, tr. 1173.
7. Francis NA, Cannings-John R, Waldron CA, Thomas-Jones E, Winfield T, Shepherd V, ... & Butler CC (2018) Oral steroids for resolution of otitis media with effusion in children (OSTRICH): A double-blinded, placebo-controlled randomised trial. The Lancet 392(10147): 557-568.
8. Aryal A, Kunwar K, Shadvar S, Kharel S, Ramasamy R, Shashidhar G ... & Nazeem T (2017) Study on steroid utilization pattern in a tertiary care teaching hospital. Indian Journal of Pharmacy Practic 10(2).
9. Bộ Y tế (2017) Thông tư số: 52/2017/TT-BYT. “Quy định về đơn thuốc và việc kê đơn thuốc hóa dược, sinh phẩm trong điều trị ngoại trị. Nhà xuất bản Y học Hà Nội.
10. Đặng Ngọc Bích (2020) Phân tích tình hình sử dụng thuốc corticoid đường uống theo quy định của Bộ Y Tế tại bệnh viện đa khoa tỉnh Kiên Giang. Luận văn thạc sĩ dược học, Trường Đại học Tây Đô.