Đánh giá mức độ đồng thuận giữa hai tiêu chuẩn Beers 2019 và STOPP phiên bản 2 khi xác định nguy cơ dùng thuốc không hợp lý tại Bệnh viện Nhân dân Gia Định

Abstract

Objective: To examine the agreement between Beers 2019 and STOPP version 2 in determining potential inappropriate medications (PIM) in elderly patients and associated factors of PIM. Subject and method: A reprospective, descriptive study was carried out on 333 medical records of inpatients aged ≥60 years, admitted at internal deparments of Gia Dinh People’s hospital from April 2020 to June 2020. PIM was identified using Beers 2019 and STOPP version 2 criteria. The degree of agreement between these 2 criteria was determined using Cohen's kappa coefficient. Result: The rates of patients with PIM based on Beers 2019 criteria and STOPP criteria version 2 were 35.4% and 33.9%, respectively. The most common PIM according to Beers criteria were benzodiazepine, metoclopramide, NSAID use in patients with heart failure, central alpha - agonists, antipsychotics. The most common PIM according to STOPP version 2 were benzodiazepine, first – generation antihistamines, central alpha – agonists, neuroleptic drugs, NSAID use in patients with reduced renal function. There is good agreement between Beers 2019 and STOPP version 2 in determining PIM (К=0.636, p<0.001). Risk of PIM increases in patients using ≥10 medications. Conclusion: Beers 2019 and STOPP version 2 have good agreement. Clinical pharmacists could make interventions based on common PIM to enhance appropriate prescription in elderly patients.