Prevention of venous thromboembolism after abdominal - pelvic tumor resection among cancer patients at the Institute of Gastroenterology Surgery - 108 Military Central Hospital

  • Tống Thanh Huyền Bệnh viện Trung ương Quân đội 108
  • Nguyễn Đức Trung Bệnh viện Trung ương Quân đội 108
  • Nguyễn Thị Liên Hương Bệnh viện Trung ương Quân đội 108
  • Nguyễn Thị Thu Thủy Trường Đại học Dược Hà Nội
  • Đào Hồng Mùi Bệnh viện Trung ương Quân đội 108

Main Article Content

Keywords

Prevention, venous thromboembolism, cancer, abdominal – pelvic tumor resection

Abstract

Objective: To analyze the current status of venous thromboembolism prevention after abdominal - pelvic tumor resection among cancer patients at the Institute of Gastroenterology Surgery - 108 Military Central Hospital. Subject and method: A prospective, descriptive, observational study of all cancer patients undergoing abdominal or pelvic tumor resection at the Institute of Gastroenterology Surgery - 108 Military Central Hospital, from 1st April 2023 to 20th April 2023. Result: The study was conducted on 86 patients. The proportion of patients using venous thromboembolism prophylaxis only accounted for 30.2% and all of which used pharmacologic thromboprophylaxis as monotherapy. In the group of patients receiving prophylaxis, all were selected appropriate prophylaxis with enoxaparin, of which the dose, time of initiation, and minimum duration of prophylaxis were consistent were 84.6%, 0% and 23.1%, respectively. All patients in the non-prophylactic group were assessed as having inadequate prophylaxis. Conclusion: Venous thromboembolism prophylaxis is not yet routine with delayed initiation of prophylactic drugs and, in most cases, shorter duration of prophylaxis than recommended. It is necessary to explore the related barriers and then propose solutions to improve the quality of treatment

Article Details

References

1. Bộ Y tế (2020) Hướng dẫn chẩn đoán và điều trị một số bệnh ung bướu.
2. Hội Tim mạch học Việt Nam (2022) Khuyến cáo về chẩn đoán, điều trị và dự phòng thuyên tắc huyết khối tĩnh mạch 2022.
3. Bahl V, Hu HM et al (2010) A validation study of a retrospective venous thromboembolism risk scoring method. Ann Surg 251(2): 344-50.
4. Falanga A, Ay C et al (2023) Venous thromboembolism in cancer patients: ESMO clinical practice guideline. Annals of Oncology 34(5):
452-467.
5. Gould MK, Garcia DA et al (2012) Prevention of VTE in nonorthopedic surgical patients: Antithrombotic Therapy and Prevention of Thrombosis, 9th ed: American College of Chest Physicians Evidence-Based Clinical Practice Guidelines. Chest 141(2): 227-277.
6. Key Nigel S, Khorana Alok A et al (2023) Venous thromboembolism prophylaxis and treatment in patients with cancer: ASCO guideline update. Journal of Clinical Oncology 41(16): 3063-3071.
7. Krell RW, Scally CP, Wong SL, Abdelsattar ZM, Birkmeyer NJ, Fegan K, Todd J, Henke PK, Campbell DA, Hendren S (2015) Variation in hospital thromboprophylaxis practices for abdominal cancer surgery. Annals of Surgical Oncology 23.
8. Streiff MB, Holmstrom B et al (2021) Cancer-associated venous thromboembolic disease, version 2.2021, nccn clinical practice guidelines in oncology. J Natl Compr Canc Netw 19(10): 1181-1201.